| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:57:00 | We found abundant GAS5 expression and a reduction in RGC density in the retinal tissues of glaucoma rats. Silencing of GAS5 led to increased EZH2 expression and decreased ABCA1 expression in RGCs. In addition, upregulation of EZH2 promoted trimethylation of lysine 27 on histone H3, thereby suppressing ABCA1 expression and eventually leading to the inhibition of RGC apoptosis. | 31608710 |
| 2019-10-19 11:40:00 | ABCA1 suppressed PDGF-induced proliferation, migration, and contraction in rat airway smooth muscle cells at least partly through TLR2/NF-kappaB/NFATc1 signaling, which might offer hope for the future treatment of airway remodeling in asthma. | 29775222 |
| 2018-06-30 11:24:00 | Increased expression of hepatic ABCA1 transporter is associated with hypercholesterolemia in a cholestatic rat model and primary biliary cholangitis patients. | 28660384 |
| 2018-04-07 11:18:00 | Advanced glycation end products affect cholesterol homeostasis by impairing ABCA1 expression on macrophages | 28704619 |
| 2017-11-25 13:39:00 | an important role for hepatic ABCA1 in regulating secretory trafficking and modulating VLDL expansion during the TG accretion phase of hepatic lipoprotein particle assembly | 28694219 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q80ZB2_RAT,
F1LNL3_RAT
UniprotKB:
Q80ZB2,
F1LNL3
UniParc:
UPI00000067BB,
UPI0004E47AD2
EMBL:
AABR07048271,
AABR07048273,
AY208182,
AABR07048272
Ensembl:
ENSRNOG00000018126
KO:
rno:313210
|
| Nucleutide sequences |
EMBL-CDS:
AAO53557.1
Ensembl_TRS:
ENSRNOT00000024564
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000024564
RefSeq:
NP_835196.1,
XP_008761932.1,
XP_008761931.1,
XP_008761930.1
|
| Others |
UniRef100:
UniRef100_F1LNL3,
UniRef100_Q80ZB2
UniRef90:
UniRef90_O95477
UniRef50:
UniRef50_O95477
UniGene:
Rn.148916,
Rn.231131
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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