| Type | Description |
|---|---|
| Definition | mitogen activated protein kinase kinase kinase 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:30:00 | Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway. | 31953451 |
| 2020-04-04 10:15:00 | Exercise triggered a crucial modulation in TAK1-dependent signaling. | 30367484 |
| 2019-06-29 11:28:00 | TAK1 mediated the phosphorylation of Ski-related novel protein N (SnoN), resulting in SnoN ubiquitination and eventual degradation, which enhanced EMT and extracellular matrix deposition to promote renal fibrosis during diabetic nephropathy. | 31028803 |
| 2019-06-01 10:49:00 | AMPKalpha phosphorylation after TLR9 activation in VSMCs appears to be an extension of traditional inflammatory signaling via TAK1 | 29348267 |
| 2018-03-17 11:28:00 | dihydrolipoic acid (DHLA) treatment improved neurofunction and alleviated inflammation through the lysosome-associated membrane protein-1/CaMKII/TAK1 pathway in early brain injury after subarachnoid hemorrhage (SAH). DHLA may provide a promising treatment to alleviate early brain injury after SAH. | 29273596 |
| Type | IDs |
|---|---|
| Synonymous | Tak1 |
| Gene |
UniProtKB-ID:
M3K7_RAT
UniprotKB:
P0C8E4
UniParc:
UPI0000250332
EMBL:
CB583299,
DN936104,
CB771642,
CK481792,
AABR03040223
Ensembl:
ENSRNOG00000047516,
ENSRNOG00000005724
KO:
rno:100910771,
rno:313121
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000007657,
ENSRNOT00000007654
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007657,
ENSRNOP00000007654
RefSeq:
XP_006238028.1,
NP_001101390.2
|
| Others |
UniRef100:
UniRef100_P0C8E4
UniRef90:
UniRef90_O43318
UniRef50:
UniRef50_O43318
UniGene:
Rn.24019
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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