| Type | Description |
|---|---|
| Definition | major histocompatibility complex, class II, DR beta 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:55:00 | Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia. | 31624234 |
| 2020-07-25 10:13:00 | In this study, molecular dynamics simulation was performed on the complexes of Top1 peptide with various HLA-DR subtypes divided into ATASSc-associated alleles (HLA-DRB1*08:02, HLA-DRB1*11:01 and HLA-DRB1*11:04), suspected allele (HLA-DRB5*01:02), and non-associated allele (HLA-DRB1*01:01). | 30679605 |
| 2018-05-12 11:50:00 | Variation at HLA-DRB5 being associated both with Parkinson's disease and Alzheimer's disease, ariation at HLA-DRB5 being associated both with Parkinson's disease and Alzheimer's disease. | 27713094 |
| 2017-06-03 10:54:00 | Case-control study in Han Chinese from the southwest of the country suggests that risk of ALS is increased by the AA genotype at rs9268856 in the HLA-DRA/HLA-DRB5 gene, but not by the SNPs rs9268877 in HLA-DRA/HLA-DRB5, rs1980493 in BTNL2 or rs302668 in RAB38/CTSC | 28131168 |
| 2017-05-27 10:53:00 | This study identified genetic overlap between Alzheimer disease and immune-mediated diseases, implicating the HLA locus and IPMK in the pathobiology of Alzheimer disease. | 27088644 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DRB5_HUMAN,
A0A2Z4LKS3_HUMAN
UniprotKB:
Q30154,
A0A2Z4LKS3
UniParc:
UPI000008AF56
EMBL:
AY141137,
Y09342,
M16955,
BC009234,
MK680934,
X87210,
U31770,
Y13727,
M17377,
MN565784,
AK314834,
FN430425,
Z83201,
AF122887,
M20429,
AL713966,
AJ271159,
M35159,
MN565795,
MN565785,
M91001,
M16954,
U59685,
AJ427352,
MG571447,
AY457037
Ensembl:
ENSG00000198502
KO:
hsa:3127
|
| Nucleutide sequences |
EMBL-CDS:
AAA36277.1,
CAB05668.1,
BAG37353.1,
AAD31766.1,
CAB71144.1,
CAD20460.1,
AAB63983.1,
AAA59791.1,
CAZ86696.1,
CAI18079.1,
CAA70524.1,
AAB52229.1,
AAA59818.1,
AAA59822.1,
AAR20446.2,
AAH09234.1,
AAN28924.1,
AAA36276.1,
CAA74055.1,
QCY59264.1,
AWX41771.1,
QHD57372.1,
QHD57371.1,
QHD57373.1
Ensembl_TRS:
ENST00000374975
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364114
RefSeq:
NP_002116.2,
XP_011512864.1
|
| Others |
UniRef100:
UniRef100_Q30154
UniRef90:
UniRef90_Q30154
UniRef50:
UniRef50_Q30154
UniGene:
Hs.485130,
Hs.534322,
Hs.696211,
Hs.736560
CCDS:
CCDS4751.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员