| Type | Description |
|---|---|
| Definition | major histocompatibility complex, class II, DR beta 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:01:00 | HLA-DR53 (DRB4 *01) associates with nickel sensitization. | 32693207 |
| 2018-03-10 11:59:00 | We developed an human cardiac alpha-myosin -induced myocarditis model in human HLA-DR4 transgenic mice that lack all mouse MHCII genes. | 28431892 |
| 2017-07-01 10:08:00 | Strong association of nontumor anti-LGI1 encephalitis with HLA-DRB4. | 28026046 |
| 2017-04-29 12:11:00 | HLA-DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of Tregs and reduced PD-1 expression may result in spontaneous activation of key immune cell subsets, such as antigen-presenting cells and CD8(+) T effectors, facilitating the induction of AIH and persistent liver damage. | 27414259 |
| 2016-07-16 11:09:00 | HLA-DRB4 affects type 1 diabetes risk and islet autoantibodies. | 26740600 |
| Type | IDs |
|---|---|
| Synonymous | DR4, DRB4, HLA-DR4B |
| Gene |
UniProtKB-ID:
DRB4_HUMAN,
X5D2U9_HUMAN
UniprotKB:
P13762,
X5D2U9
UniParc:
UPI00000725D8
EMBL:
MN565803,
BX571807,
MG571445,
AH011268,
MK680935,
DQ284431,
MK610120,
AY394720,
BX927235,
MK501757,
Y09313,
MH892051,
MH733610,
KJ657695,
MN565798,
MK854710,
MK610118,
MN565797,
MK192689,
MK170166,
MK170167,
MG571444,
MN565791,
MK170172,
MN565794,
MH892052,
AK292151,
MK610119,
MH733609,
BC005312,
M15178,
BX120007,
MH395140,
KJ657697,
AB107960,
CR788250,
MH892056,
MN565792,
CR933859,
MN565804,
AF361549,
M20555,
KJ657694,
M16942,
GQ891550,
AH012539,
AF361548,
KJ657696,
MK170165
Ensembl:
ENSG00000227357,
ENSG00000231021
KO:
hsa:3126
|
| Nucleutide sequences |
EMBL-CDS:
AAH05312.1,
CAA70497.1,
AAA36296.1,
AAQ96922.1,
ACX50637.1,
AAO43051.1,
AAA35995.1,
ABC66198.1,
AAA59830.1,
AAM00253.1,
BAF84840.1,
AAL48256.1,
BAC75547.1,
AAM00252.1,
QHD57390.1,
QCY59247.1,
QDC22494.1,
QCY59250.1,
AHW47953.1,
QCC20780.1,
QHD57385.1,
QCF28404.1,
AHW47970.1,
QHD57386.1,
QHD57391.1,
AUV47237.2,
QHD57388.1,
QDC22495.1,
QHD57387.1,
QCF28400.1,
AXA98027.1,
QCY59249.1,
QCZ35729.1,
AUV47236.2,
QCF28399.1,
QCY59248.1,
QCC20781.1,
QDC22501.1,
QDC22496.1,
QHD57384.1,
QCY59233.1,
AHW47936.1,
AHW47919.1,
QCY59265.1
Ensembl_TRS:
ENST00000411565,
ENST00000457451,
ENST00000457451
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000410857,
ENSP00000412031,
ENSP00000412031
RefSeq:
NP_068818.4
|
| Others |
UniRef100:
UniRef100_P13762
UniRef90:
UniRef90_P13762
UniRef50:
UniRef50_P01920
UniGene:
Hs.534322,
Hs.696211,
Hs.716081,
Hs.723344
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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