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3125 HLA-DRB3

3125

HLA-DRB3

major histocompatibility complex, class II, DR beta 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition major histocompatibility complex, class II, DR beta 3

研究结论

Date Results Publications
2017-06-24 12:36:00 In contrast to HLA-DRB4*01:01P, the inheritance of HLA-DRB3*01:01 is strongly associated with the propensity for mounting a humoral immune response against fetal HPA-1a antigen. 28019029
2017-06-03 10:26:00 our findings provide clear evidence that the HLA-DRB1*15:01 and HLA-DRB3*02:02 alleles independently and strongly associate with phospholipase A2 receptor related idiopathic membranous nephropathy in the Chinese population 28028136
2017-02-18 10:49:00 The first time that the haplotypes A33-DR3 and A33-DR9 were found with an enhanced predisposition to type 1 diabetes in Han Chinese. 27181214
2016-07-16 11:09:00 HLA-DRB3 affects type 1 diabetes risk and islet autoantibodies. 26740600
2016-03-26 10:26:00 this mouse model unravels a critical role for HLA-DR3 in generating an autoimmune response to SmD and lupus nephritis in the NZM2328 background. 26475924

名称对应

Type IDs
Synonymous DRB3, HLA-DPB1, HLA-DR1B, HLA-DR3B
Gene
UniProtKB-ID: DRB3_HUMAN, A0A4D6G1L1_HUMAN
UniprotKB: P79483, A0A4D6G1L1
UniParc: UPI000007150D
EMBL: AJ242862, A06800, MK854713, AF148518, AF461431, U95819, FN424162, Y13715, U36826, AL662842, EU873153, AF208485, X95760, X04058, V00522, X86977, MK328511, AY958608, AF208484, BC106057, AY138123, CR788283, AJ001255, AF177216, AY291205, Y08063, AF026467, EU873151, AF028012, AM413002, MN565788, AF192259, AJ564210, MK854714, DQ311653, AF152845, AJ290395, AM747470, AF199236, EU873152, AJ242860, AY271986, AF081677, M17380, BC008987, AF427138, X04055, FN424163, AF455114, Z84814, FJ515276, U94590, MK854711, AL929581, AJ315477, MH733607, AF192258, Y10180, U66825, AF361865, AY042679, X91639
Ensembl: ENSG00000231679, ENSG00000196101
KO: hsa:3125
Nucleutide sequences
EMBL-CDS: CAC27417.1, AAF23165.1, CAA71253.1, CAA23781.1, AAF26358.1, AAF67837.1, AAC05599.1, ACF33221.1, ACF33222.1, AAL66370.1, AAD00819.1, CAA65066.1, AAH08987.1, ACL50609.1, CAZ66795.1, AAB94614.1, AAF13065.2, AAN15205.1, AAK94514.1, CAB06607.1, AAB63531.1, AAL26538.1, CAA00596.1, CAB62392.1, ACF33223.1, AAF26359.1, CAA74043.1, AAD53911.1, CAD91915.2, CAC86562.1, AAL57866.1, CAO00528.1, CAB62390.1, AAP23230.1, AAC32202.1, AAP43643.1, CAA69301.1, AAI06058.1, AAD43828.1, CAZ66766.1, ABC33924.1, AAD45286.1, AAK38297.1, AAA59804.1, CAL85628.1, AAB53324.1, CAA04629.1, AAF23166.1, AAY28717.1, QCZ35730.1, QCZ35732.1, QHD57375.1, QCY59241.1, QCC20778.1, QCZ35733.1
Ensembl_TRS: ENST00000307137, ENST00000383126
Protein sequencees
Ensembl_PRO: ENSP00000372607, ENSP00000302517
RefSeq: NP_072049.2
Others
UniRef100: UniRef100_P79483
UniRef90: UniRef90_P79483
UniRef50: UniRef50_P79483
UniGene: Hs.696211

全选

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研究热度

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