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31248 sgg

31248

sgg

shaggy

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition shaggy

研究结论

Date Results Publications
2020-10-24 14:11:00 Characterisation of protein isoforms encoded by the Drosophila Glycogen Synthase Kinase 3 gene shaggy. 32760087
2017-07-29 11:25:00 Our findings demonstrated that lovastatin restored LRRK2-G2019S neurite degeneration by augmenting Akt/NRF2 pathway and inhibiting downstream GSK3b activity, which decreased phospho-tau levels. We suggested that lovastatin is a potential disease-modifying agent for LRRK2-G2019S parkinsonism. 26931464
2016-06-11 11:56:00 Mitochondrial function leads to extensive glycogen accumulation late in oogenesis and is required for the developmental competence of the oocyte. Decreased insulin signaling initiates ETC remodeling and mitochondrial respiratory quiescence through glycogen synthase kinase 3 (GSK3). 26824655
2016-05-21 10:25:00 Drosophila-based findings highlight an apical role for Hyd and Sgg in initiating Hedgehog signalling, which could also be evolutionarily conserved in mammals 26334301
2015-11-28 10:45:00 Results show that downregulation of GSK3 promotes synapse formation in Drosophila neurons. However in rats hippocampal neurons, GSK3 inhibition yields to decrease of synapses in young neurons culture and the opposite in aged culture. 25764078

名称对应

Type IDs
Synonymous CG2621, DMSGG3, DMZ3K25Z, Dm Zw3, Dmel\CG2621, Dmsgg3, EG:155E2.3, EG:BACR7C10.8, GSK, GSK-3, GSK-3B, GSK-3beta, GSK-3betaSgg, GSK3, GSK3-beta, GSK3A, GSK3Beta, GSK3beta, GSK3beta/SGG, GSK3betagr, GSKbeta, Gsk-3, Gsk-3beta, Gsk3, Gsk3beta, SGG, SGG/GSK3b, SHAGGY, Sgg, Sgg/Zw3/GSK3, ZW-3, ZW3, Zw-3, Zw3, Zw3-sh, Zw3/GSK3, Zw3[sgg], anon-WO03040301.254, gsk3, l(1)3Ba, l(1)G0055, l(1)G0183, l(1)G0263, l(1)G0335, l(1)zw3, sgg-1, sgg-zw3, sgg/zw3, sgg10, sgg39, sgg46, zw-3, zw3, zw3(sgg), zw3/GSK3beta, zw3/sgg, zw3[sgg], zw[3]
Gene
UniProtKB-ID: SGG_DROME, Q7KVY5_DROME, A4V3W2_DROME, C0PUX5_DROME, M9PGC4_DROME, A8JUV9_DROME, H5V852_DROME, B6IDN4_DROME, Q0KHW6_DROME, A4V3W1_DROME, M9PGV7_DROME
UniprotKB: P18431, Q7KVY5, A4V3W2, C0PUX5, M9PGC4, A8JUV9, H5V852, B6IDN4, Q0KHW6, A4V3W1, M9PGV7
UniParc: UPI00001E280B, UPI0000167F96, UPI000013591B, UPI00029416A2, UPI00000014CE, UPI00015D9B27, UPI0002945C99, UPI000195D70F, UPI000294607C, UPI000034DDBE, UPI000002B384
EMBL: AY122193, AL024485, AE014298, AL034544, X70863, AL121804, X70862, X54005, BT072831, X54006, X53332, BT050474, X70864, BT133153, AY119664, X70866, X70865
EnsemblGenome: FBgn0003371
KO: dme:Dmel_CG2621
Nucleutide sequences
EMBL-CDS: CAB65860.1, CAB72296.1, AAN09082.1, CAA37952.1, CAA50215.1, CAA19676.1, CAA50214.1, CAA37419.1, AAM52705.1, CAA50212.1, AAM50318.1, AAN09083.1, CAA50216.1, AAS65255.1, CAA37951.1, CAA50213.1, AAF45801.2, ACZ95186.1, AAS65256.1, AAS65254.1, AAN09085.1, AAN09086.1, AAN09084.1, AAS65253.1, ACN62434.1, ACZ95187.1, AGB95038.1, ABW09331.1, AEZ02846.1, ACJ13181.1, ABI30966.2, AAS65252.1, AGB95039.1
Gene_ORFName: CG2621, Dmel_CG2621, CG2621, Dmel_CG2621, CG2621, Dmel_CG2621, CG2621, Dmel_CG2621, CG2621, Dmel_CG2621, CG2621, CG2621, Dmel_CG2621, CG2621, Dmel_CG2621, CG2621, Dmel_CG2621
EnsemblGenome_TRS: FBtr0070468, FBtr0070467, FBtr0070466, FBtr0070473, FBtr0070475, FBtr0070474, FBtr0070472, FBtr0070469, FBtr0070470, FBtr0301966, FBtr0070476, FBtr0070472, FBtr0070466, FBtr0070470, FBtr0070473, FBtr0070469, FBtr0070468, FBtr0302185, FBtr0331751, FBtr0112828, FBtr0070471, FBtr0070475, FBtr0331753, FBtr0070467, FBtr0070474, FBtr0331752
Protein sequencees
EnsemblGenome_PRO: FBpp0089158, FBpp0089160, FBpp0070451, FBpp0070450, FBpp0089159, FBpp0070449, FBpp0070453, FBpp0089162, FBpp0070452, FBpp0291178, FBpp0089161, FBpp0089162, FBpp0089158, FBpp0070453, FBpp0070452, FBpp0070449, FBpp0070451, FBpp0291395, FBpp0304139, FBpp0111741, FBpp0070454, FBpp0089160, FBpp0304141, FBpp0089159, FBpp0070450, FBpp0304140
RefSeq: NP_001162650.1, NP_001096870.1, NP_476715.1, NP_996334.1, NP_599105.1, NP_996337.1, NP_726823.1, NP_996338.1, NP_476714.1, NP_726822.1, NP_476716.2, NP_001259193.1, NP_996336.1, NP_996335.1, NP_001162649.1, NP_001259192.1, NP_001036259.2
Others
UniRef100: UniRef100_Q0KHW6, UniRef100_B6IDN4, UniRef100_H5V852, UniRef100_A4V3W1, UniRef100_M9PGV7, UniRef100_A8JUV9, UniRef100_P18431, UniRef100_C0PUX5, UniRef100_M9PGC4
UniRef90: UniRef90_P18431, UniRef90_P18431-1, UniRef90_C0PUX5, UniRef90_A8JUV9
UniRef50: UniRef50_C0PUX5, UniRef50_P18431, UniRef50_A8JUV9, UniRef50_P18431-1
UniGene: Dm.7795

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研究热度

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