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3122 HLA-DRA

3122

HLA-DRA

major histocompatibility complex, class II, DR alpha

protein-coding

Homo sapiens

基因描述

Type Description
Definition major histocompatibility complex, class II, DR alpha

研究结论

Date Results Publications
2020-11-21 13:21:00 The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide. 31237711
2020-07-25 11:28:00 Loss of HLA-DR expression is associated with colorectal cancer development. 32306077
2020-05-09 12:12:00 Cd64 is up-regulated in neutrophils, but HLA-DR antigens are down-regulated in monocytes in septic shock patients. 31082373
2020-04-11 11:26:00 Identified an intergenic variant between HLADRA and HLA-DRB that is associated with Ulcerative Colitis prognosis, but not with susceptibility, and confirmed its clinical impact on 30-year outcomes. 29905830
2020-02-15 12:55:00 We report that risk for type 1 diabetes in HLA-DR3 homozygotes is increased significantly by a previously unreported haplotype of three single nucleotide polymorphisms (SNPs) within the first intron of HLA-DRA1. 30962219

名称对应

Type IDs
Synonymous HLA-DRA1
Gene
UniProtKB-ID: DRA_HUMAN, A0A0G2JMH6_HUMAN
UniprotKB: P01903, A0A0G2JMH6
UniParc: UPI000004493F, UPI000000160D
EMBL: CH471081, KY497344, BC071659, KY497338, KY497355, Z84814, BC032350, J00203, J00204, KY497347, V00523, CR457013, BX120007, X00274, KY497339, AL670296, AL662796, KY497342, AF481359, KY497353, M60334, KY497345, J00194, K01171, J00201, AL935032
Ensembl: ENSG00000206308, ENSG00000277263, ENSG00000234794, ENSG00000204287, ENSG00000228987, ENSG00000230726, ENSG00000227993, ENSG00000226260
KO: hsa:3122
Nucleutide sequences
EMBL-CDS: AAH71659.1, CAG33294.1, AAA36275.1, CAA25076.1, AAA59783.1, AAH32350.1, EAX03630.1, AAA36301.1, AAA36302.1, CAB06609.1, AAA59785.1, CAA23782.1, AAO23887.1, ARB08434.1, ARB08432.1, ARB08435.1, ARB08437.1, ARB08428.1, ARB08445.1, ARB08443.1, ARB08429.1
Ensembl_TRS: ENST00000383259, ENST00000395388, ENST00000442960, ENST00000414698, ENST00000383127, ENST00000411524, ENST00000416883, ENST00000613328
Protein sequencees
Ensembl_PRO: ENSP00000405295, ENSP00000378786, ENSP00000410443, ENSP00000372608, ENSP00000372746, ENSP00000402951, ENSP00000404533, ENSP00000479287
RefSeq: NP_061984.2
Others
UniRef100: UniRef100_A0A0G2JMH6, UniRef100_P01903
UniRef90: UniRef90_P01903
UniRef50: UniRef50_P01903
UniGene: Hs.520048
CCDS: CCDS4750.1

全选

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研究热度

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