| Type | Description |
|---|---|
| Definition | insomniac |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:39:00 | Study identified insomniac (inc), a putative adaptor for the Cullin-3 (Cul3) ubiquitin ligase complex, which together with Cul3 is essential for normal sleep regulation. Interestingly, Inc and Cul3 rapidly accumulate at postsynaptic compartments following acute receptor inhibition and are required for a local increase in mono-ubiquitination. | 31278365 |
| 2017-07-01 10:10:00 | inc mutants exhibit defects in synaptic structure and physiology, indicating that Inc is essential for both sleep and synaptic function. Inc and its mouse orthologs exhibit striking biochemical and functional interchangeability within Cul3 complexes. | 28558011 |
| 2017-02-04 10:47:00 | Data show that insomniac protein (INC) recognize its potential partners Cul3 and dGRASP. | 27678190 |
| 2013-03-23 10:31:00 | these results establish inc and Cul3 as important new players in setting the sleep homeostat and a dopaminergic arousal pathway in Drosophila. | 23055946 |
| Type | IDs |
|---|---|
| Synonymous | CG14783, CG14784, CG32810, Dmel\CG32810, EG:196F3.2, INC, ins |
| Gene |
UniProtKB-ID:
Q9W579_DROME
UniprotKB:
Q9W579
UniParc:
UPI000007F622
EMBL:
AE014298,
BT126052
EnsemblGenome:
FBgn0025394
KO:
dme:Dmel_CG32810
|
| Nucleutide sequences |
EMBL-CDS:
AAF45642.1,
AHN59258.1,
ADY17751.1,
AHN59257.1
Gene_ORFName:
CG32810,
Dmel_CG32810
EnsemblGenome_TRS:
FBtr0070260,
FBtr0339591,
FBtr0339590
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0070250,
FBpp0308663,
FBpp0308662
RefSeq:
NP_569926.2,
NP_001284787.1,
NP_001284786.1
|
| Others |
UniRef100:
UniRef100_Q9W579
UniRef90:
UniRef90_Q9W579
UniRef50:
UniRef50_Q9W579
UniGene:
Dm.15
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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