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3109 HLA-DMB

3109

HLA-DMB

major histocompatibility complex, class II, DM beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition major histocompatibility complex, class II, DM beta

研究结论

Date Results Publications
2015-09-12 11:10:00 This study provides novel insights into how HLA-DM efficiently catalyzes peptide loading during antigen presentation. 26062997
2015-06-27 13:18:00 Data suggest that antigen processing by MHC class II HLA-DMB antigen is a target pathway in the pathogenesis of HIV-related Kaposi's sarcoma. 25008864
2013-03-02 10:52:00 The structure of the HLA-DM-HLA-DR complex shows major rearrangements of the HLA-DR peptide-binding groove. 23260142
2012-08-11 10:32:00 DMA*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans 22309257
2011-09-03 11:39:00 Overexpression of HLA-DM at the plasma membrane of dendritic cells improves quantitatively, but also qualitatively, the presentation of CD4-expressing T cell epitopes in cellular vaccine therapies for cancer. 21622867

名称对应

Type IDs
Synonymous D6S221E, RING7
Gene
UniProtKB-ID: DMB_HUMAN, A0A1V0E3P2_HUMAN
UniprotKB: P28068, A0A1V0E3P2
UniParc: UPI00000012A6, UPI0000140DCC
EMBL: AL935042, AL645941, Z24750, CR759798, Z23139, KY497294, CR936913, U15085, AL662845, BX088556, BC027175, KY497277, U16762, KY497287, U00700, BX927138, X87344, CH471081, AF072680, X76776, Z24751, AF134890, KY497284, CR752645, AY645722
Ensembl: ENSG00000239329, ENSG00000226264, ENSG00000241674, ENSG00000242386, ENSG00000242574, ENSG00000242092, ENSG00000234154, ENSG00000241296
KO: hsa:3109
Nucleutide sequences
EMBL-CDS: CAA60782.1, AAC26112.1, AAV97947.1, AAA03296.1, AAB60387.1, AAD30279.1, CAA80670.1, CAA54171.1, EAX03657.1, AAC50514.1, AAH27175.1, ARB08374.1, ARB08367.1, ARB08377.1, ARB08384.1
Ensembl_TRS: ENST00000412948, ENST00000450897, ENST00000418107, ENST00000395312, ENST00000424822, ENST00000440078, ENST00000383231, ENST00000428420
Protein sequencees
Ensembl_PRO: ENSP00000393646, ENSP00000413471, ENSP00000408453, ENSP00000411321, ENSP00000372718, ENSP00000398890, ENSP00000414817, ENSP00000378723
RefSeq: NP_002109.2
Others
UniRef100: UniRef100_A0A1V0E3P2, UniRef100_P28068
UniRef90: UniRef90_P28068, UniRef90_G3RQJ2
UniRef50: UniRef50_P28068
UniGene: Hs.351279
CCDS: CCDS4760.1

全选

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研究热度

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