| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2014-05-31 11:08:00 | Following cAMP elevation, neuritogenic cyclic AMP sensor/Rapgef2 is activated for signaling to ERK to mediate neuritogenesis, whereas Epac2 is activated for signaling to the MAP kinase p38 to mediate growth arrest. | 24567337 |
| 2014-01-25 11:09:00 | Data indicate that knockdown of Rapgef2 ablates cAMP-dependent ERK activation and neuritogenesis in neuronal cell line Neuroscreen-1 (NS-1). | 23800469 |
| Type | IDs |
|---|---|
| Synonymous | PDZ-GEF1, RA-GEF-1, nRap GEP |
| Gene |
UniProtKB-ID:
RPGF2_RAT,
A0A0G2JU11_RAT,
A0A0A0MP77_RAT
UniprotKB:
F1M386,
A0A0G2JU11,
A0A0A0MP77
UniParc:
UPI0004E4811F,
UPI000154FC31,
UPI000237497F
EMBL:
AABR07011956,
CH473976,
AABR07011957,
AABR07011958
Ensembl:
ENSRNOG00000021581
KO:
rno:310533
|
| Nucleutide sequences |
EMBL-CDS:
EDM00875.1
Ensembl_TRS:
ENSRNOT00000029340,
ENSRNOT00000091135,
ENSRNOT00000012792
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000037119,
ENSRNOP00000068918,
ENSRNOP00000012792
RefSeq:
NP_001101154.1,
XP_008759318.1,
XP_006232575.1,
XP_008759317.1,
XP_008759320.1,
XP_006232574.1,
XP_008759319.1,
XP_008759314.1,
XP_008759316.1,
XP_006232573.2,
XP_008759315.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JU11,
UniRef100_F1M386,
UniRef100_A0A0A0MP77
UniRef90:
UniRef90_Q9Y4G8
UniRef50:
UniRef50_Q9Y4G8
UniGene:
Rn.23121
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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