| Type | Description |
|---|---|
| Definition | zinc finger and BTB domain containing 48 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Clinical and Prognostic Significance of TZAP Expression in Cervical Cancer. | 32344888 |
| 2020-06-06 13:30:00 | The ZBTB48 (TZAP) mutation (c.1272 G > A, L424L) was found in 7.8% of128 breast cancer (BC) patients and was associated with the N0 stage. BCs with the TZAP mutation had longer telomeres than those without this mutation. Survival analysis showed that the TZAP mutation resulted in poorer overall survival. | 31752241 |
| 2018-02-24 11:43:00 | study demonstrate through a combination of RNAseq, ChIPseq and expression proteomics experiments that ZBTB48 acts as a transcriptional activator on a small set of target genes, including mitochondrial fission process 1 (MTFP1). This discovery places ZBTB48 at the interface of telomere length regulation, transcriptional control and mitochondrial metabolism | 28500257 |
| 2017-09-23 11:01:00 | this study describes a specific telomere-associated protein: TZAP (telomeric zinc finger-associated protein). Binding of TZAP to long telomeres represents the switch that triggers telomere trimming, setting the upper limit of telomere length. | 28082411 |
| 2014-05-03 10:50:00 | HKR3 potently activated the transcription of the tumor suppressor gene ARF by acting on the proximal promoter region (bp, -149 approximately +53), which contains Sp1 and FBI-1 binding elements (FREs). | 24382891 |
| Type | IDs |
|---|---|
| Synonymous | HKR3, TZAP, ZNF855, pp9964 |
| Gene |
UniProtKB-ID:
TZAP_HUMAN,
A8K291_HUMAN,
B2R702_HUMAN
UniprotKB:
P10074,
A8K291,
B2R702
UniParc:
UPI000012C932,
UPI00017505BD,
UPI00015DA4FC
EMBL:
AK290156,
AK312786,
U45324,
AL591866,
M20677,
L16896,
U45325,
BC013573
Ensembl:
ENSG00000204859
KO:
hsa:3104
|
| Nucleutide sequences |
EMBL-CDS:
AAH13573.1,
AAA35989.1,
AAA65124.1,
AAB08973.1,
BAF82845.1,
BAG35649.1
Ensembl_TRS:
ENST00000377674
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366902
RefSeq:
XP_016856600.1,
XP_016856603.1,
NP_001265576.1,
XP_016856599.1,
XP_016856601.1,
XP_016856602.1,
NP_001265577.1,
NP_005332.1
|
| Others |
UniRef100:
UniRef100_A8K291,
UniRef100_P10074,
UniRef100_B2R702
UniRef90:
UniRef90_P10074
UniRef50:
UniRef50_P10074
UniGene:
Hs.502330
CCDS:
CCDS84.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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