| Type | Description |
|---|---|
| Definition | RPTOR independent companion of MTOR, complex 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | Overexpression of Rictor in the injured spinal cord promotes functional recovery in a rat model of spinal cord injury. | 32232913 |
| 2020-05-09 10:28:00 | upregulation of miR-424 inhibited Rictor through Akt signaling in renal tissue of diabetic nephropathy rats and high-glucose-treated human glomerular mesangial cells. | 30637733 |
| 2018-02-24 10:17:00 | Study examined mTOR variables, with attention to mTORC2 (Rictor), in Alzheimer's disease (AD) brain samples and in two mouse models, and made comparisons with results from cell- and in vitro-based experiments where Abeta is either expressed or peptide added. Authors conclude that striking a new balance by restoring mTORC2 abundance and/or inhibition of mTORC1 has therapeutic potential in AD. | 28035937 |
| 2016-06-11 10:11:00 | Study suggests that Rictor/mTORC2 signaling activation mediates TGFbeta1-induced fibroblast activation and contributes to the development of kidney fibrosis. | 25970154 |
| 2014-05-03 12:32:00 | These data provide a novel mechanistic link of Nox4-dependent activation of mTORC2 via the energy sensor AMP-activated protein kinase to increased proliferation and survival of PAVSMCs in pulmonary artery hypertension. | 24270265 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1M4J0_RAT
UniprotKB:
F1M4J0
UniParc:
UPI0004E4739C
EMBL:
AABR07008399,
AABR07008398
Ensembl:
ENSRNOG00000011341
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000029565
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000030782
RefSeq:
XP_001055633.4,
XP_008759030.1,
XP_008773303.1,
XP_008759029.1,
XP_008773302.1,
XP_008759028.1
|
| Others |
UniRef100:
UniRef100_F1M4J0
UniRef90:
UniRef90_Q6R327
UniRef50:
UniRef50_Q6R327
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
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