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30975 ewg

30975

ewg

erect wing

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition erect wing

研究结论

Date Results Publications
2017-12-30 10:53:00 we show that Ewg repression of Cyclin E expression is required for the arrest of myoblast proliferation and initiate myoblast fusion and terminal differentiation 27039019
2017-08-05 11:49:00 in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers 28708826
2017-07-29 10:37:00 Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap 'n' collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies. Our observations indicate that activation of the Nrf1/Nrf2 pathway is a viable option for pharmacological intervention in SBMA and potentially other polyglutamine diseases. 26962150
2014-08-23 10:47:00 Mitochondrial fusion is regulated spatiotemporally by Ewg through Opa1-like during indirect flight muscles differentiation and growth. 24198395
2013-11-16 10:04:00 ewg regulates mutually exclusive R8 rhodopsin expression. 23850772

名称对应

Type IDs
Synonymous CG3114, Dmel\CG3114, EC3, EG:BACR37P7.7, EWG, Ewg, NRF-1, l(1)1Ag, l(1)DA659, l(1)EC3, l(1)EC3f, l(1)VA720, l[EC3]
Gene
UniProtKB-ID: EWG_DROME, M9PGI0_DROME, M9NEL5_DROME, M9PGB3_DROME, M9NE19_DROME, M9PG44_DROME
UniprotKB: Q24312, M9PGI0, M9NEL5, M9PGB3, M9NE19, M9PG44
UniParc: UPI00004ED44D, UPI0002ADBCB0, UPI00004ED44B, UPI000237F724, UPI00004ED449, UPI000012A2B0, UPI00004ED44A, UPI0002ADBDC9, UPI0002ADBC36, UPI0000167FA3, UPI000237F725, UPI00004ED44C
EMBL: AY089609, AE014298, L11345, AL050231, AF135590
EnsemblGenome: FBgn0005427
KO: dme:Dmel_CG3114
Nucleutide sequences
EMBL-CDS: AAX52467.1, AAF45491.5, AAX52470.1, AAA28478.1, AAX52468.1, AAX52471.1, CAB43325.1, AAL90347.1, AAF45492.5, AAD34460.1, AAX52469.1, AAX52466.1, AGB94939.1, AFH07160.1, AGB94940.1, AFH07159.1, AGB94938.1
Gene_ORFName: CG3114, Dmel_CG3114, CG3114, CG3114, Dmel_CG3114, Dmel_CG3114, CG3114, Dmel_CG3114, CG3114, CG3114, Dmel_CG3114
EnsemblGenome_TRS: FBtr0100581, FBtr0100579, FBtr0100580, FBtr0100582, FBtr0089442, FBtr0100577, FBtr0089441, FBtr0100578, FBtr0332977, FBtr0308209, FBtr0332978, FBtr0308208, FBtr0332976
Protein sequencees
EnsemblGenome_PRO: FBpp0100032, FBpp0100033, FBpp0088456, FBpp0100035, FBpp0100036, FBpp0088457, FBpp0100034, FBpp0100037, FBpp0305193, FBpp0300529, FBpp0305194, FBpp0300528, FBpp0305192
RefSeq: NP_001259093.1, NP_726660.3, NP_001259092.1, NP_001014711.1, NP_001014709.1, NP_476892.4, NP_001014710.1, NP_001014708.1, NP_001245443.1, NP_001014707.1, NP_001245444.1, NP_001014712.1, NP_001259094.1
Others
UniRef100: UniRef100_M9PGB3, UniRef100_Q24312, UniRef100_M9PG44, UniRef100_M9NE19, UniRef100_M9PGI0, UniRef100_M9NEL5
UniRef90: UniRef90_Q24312-9, UniRef90_Q24312, UniRef90_M9PG44
UniRef50: UniRef50_Q24312-9, UniRef50_Q24312
UniGene: Dm.4971

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