Mdc1 - mediator of DNA damage checkpoint 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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309595 Mdc1

基因描述

Type	Description
Definition	mediator of DNA damage checkpoint 1

名称对应

Type	IDs
Gene	UniProtKB-ID: MDC1_RAT UniprotKB: Q5U2M8 UniParc: UPI000053E854 EMBL: BX883048, BC085955 Ensembl: ENSRNOG00000032813 KO: rno:309595
Nucleutide sequences	EMBL-CDS: AAH85955.1, CAE84032.1 Ensembl_TRS: ENSRNOT00000046798
Protein sequencees	Ensembl_PRO: ENSRNOP00000049009 RefSeq: NP_001159747.1
Others	UniRef100: UniRef100_Q5U2M8 UniRef90: UniRef90_Q5U2M8 UniRef50: UniRef50_Q5PSV9 UniGene: Rn.106312

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29656893	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity. Cell Rajat Gupta , Kumar Somyajit , Takeo Narita , Elina Maskey , Andre Stanlie , Magdalena Kremer , Dimitris Typas , Michael Lammers , Niels Mailand , Andre Nussenzweig , Jiri Lukas , Chunaram Choudhary	2018-05-03	-
24550317	PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair. Proc. Natl. Acad. Sci. U.S.A. Hanan Khoury-Haddad , Noga Guttmann-Raviv , Inbal Ipenberg , David Huggins , Anand D Jeyasekharan , Nabieh Ayoub	2014-02-18	-
24217620	The histone demethylase LSD1/KDM1A promotes the DNA damage response. J. Cell Biol. Nima Mosammaparast , Haeyoung Kim , Benoit Laurent , Yu Zhao , Hui Jun Lim , Mona C Majid , Sebastian Dango , Yuying Luo , Kristina Hempel , Mathew E Sowa , Steven P Gygi , Hanno Steen , J Wade Harper , Bruce Yankner , Yang Shi	2013-11-11	Atm, Rcor1, Mdc1, Trp53bp1, Gmnn, Cdt1, Rnf168, Kdm1a, RNF168, KDM1A, RCOR1, ATM, GMNN, PHF21A, CDT1, MDC1
24002223	Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat. Rev. Mol. Cell Biol. Stephanie Panier , Daniel Durocher	2013-10-01	Vcp, Ubr5, Ppp6c, Ppp4c, Ppp2ca, Ppm1d, Usp16, Rnf4, Otub1, Pias1, Mdc1, Psmd14, L3mbtl1, Eya3, Kdm4a, Usp44, Trip12, Brcc3, Pias4, Usp3, Baz1b, H2afx, Eya1
23569343	Loss of BRCA1 expression leads to worse survival in patients with gastric carcinoma. World J. Gastroenterol. Zi-Zhen Zhang , Yuan Jie Charles Liu , Xiao-Lu Yin , Ping Zhan , Yi Gu , Xing-Zhi Ni	2013-03-28	-
23642229	Readout of epigenetic modifications. Annu. Rev. Biochem. Dinshaw J Patel , Zhanxin Wang	2013-01-01	Ywhaz, Ing2, Sgf29, Phf1, Rag2, Tp53bp1, Phf19, Dpf3, Brf1, Cbx5, Kat2a, Bptf, Mcph1, Chd1, Mdc1, L3mbtl1, Orc1, Kdm4a, Uhrf1, Taf1, Ehmt2, Wdr5, Trim33, Trim24, Birc5
23039116	HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Genes Cells Hiroshi Kogo , Makiko Tsutsumi , Hidehito Inagaki , Tamae Ohye , Hiroshi Kiyonari , Hiroki Kurahashi	2012-11-01	Brca1, H2afx, Kit, Sycp3, Mdc1, Atr, Spo11, Hormad2
21853275	NFBD1/MDC1 is a protein of oncogenic potential in human cervical cancer. Mol. Cell. Biochem. Chengfu Yuan , Youquan Bu , Changdong Wang , Faping Yi , Zhengmei Yang , Xiuning Huang , Li Cheng , Geli Liu , Yong Wang , Fangzhou Song	2012-01-01	-
21533982	ATM protein kinase: the linchpin of cellular defenses to stress. Cell Mol Life Sci Shahzad Bhatti , Sergei Kozlov , Ammad Ahmad Farooqi , Ali Naqi , Martin Lavin , Kum Kum Khanna	2011-09-01	-
21293379	MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature Huadong Pei , Lindsey Zhang , Kuntian Luo , Yuxin Qin , Marta Chesi , Frances Fei , P Leif Bergsagel , Liewei Wang , Zhongsheng You , Zhenkun Lou	2011-02-03	-

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