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30957 Mapk8ip3

30957

Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

protein-coding

Mus musculus

基因描述

Type Description
Definition mitogen-activated protein kinase 8 interacting protein 3

研究结论

Date Results Publications
2021-01-09 13:31:00 c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1 is a critical regulator for arthritis progression by meditating inflammation in mice model. 32062074
2018-12-01 10:13:00 JIP3-KO mice after aortic banding exhibited attenuated cardiac function, reduced fibrosis levels and decreased hypertrophic marker proteins. Loss of JIP3 also ameliorated oxidative stress, inflammatory response, apoptosis and endoplasmic reticulum (ER) stress in hearts. 29604277
2018-03-31 10:37:00 JIP3 absence is associated with decreased lipogenesis, oxidative stress and inflammation, supplying a new target for nonalcoholic fatty liver disease treatment. 29454969
2017-10-07 13:17:00 These results establish the critical role of JIP3-dependent axonal lysosome transport in regulating amyloidogenic amyloid precursor protein processing and support a model wherein Abeta production is amplified by plaque-induced axonal lysosome transport defects. 28784610
2017-06-24 10:55:00 Data show that c-Jun NH2-terminal kinase (JNK)-interacting protein-3 (JIP3) participates in the migration of cortical neurons during cortical development by mediating TrkB receptor axonal anterograde transport. 28259553

名称对应

Type IDs
Synonymous BB120594, D17Wsu15e, JIP-3, JSAP1, JSAP1a, JSAP1b, JSAP1c, JSAP1d, Jip3, Syd2, mKIAA1066
Gene
UniProtKB-ID: JIP3_MOUSE, Q3UYC3_MOUSE, Q3UHB5_MOUSE, E9Q6B6_MOUSE, Q6P1F1_MOUSE, E9Q6E0_MOUSE
UniprotKB: Q9ESN9, Q3UYC3, Q3UHB5, E9Q6B6, Q6P1F1, E9Q6E0
UniParc: UPI00005ABAFB, UPI000002AC63, UPI000002AC64, UPI000002785B, UPI000002AC62, UPI000164C316, UPI000164C321, UPI000002AC60, UPI0000232A06, UPI000002AC61
EMBL: AB043125, AB043129, AB005662, AK134797, AK147477, AB043123, AB043124, BC065105, AC166102, AF262046, BC060603, BC004003, AF178637, AF178636
Ensembl: ENSMUSG00000024163
KO: mmu:30957
Nucleutide sequences
EMBL-CDS: AAF26842.1, BAB16675.1, BAA85874.1, AAF26843.1, AAH60603.1, AAG36931.1, BAB16674.1, BAB16685.1, AAH04003.1, BAB16676.1, BAE22289.1, BAE27942.1, AAH65105.1
Ensembl_TRS: ENSMUST00000088345, ENSMUST00000146923, ENSMUST00000117509, ENSMUST00000115228, ENSMUST00000120035, ENSMUST00000119115, ENSMUST00000121787, ENSMUST00000121723
Protein sequencees
Ensembl_PRO: ENSMUSP00000112712, ENSMUSP00000114802, ENSMUSP00000114084, ENSMUSP00000085683, ENSMUSP00000110883, ENSMUSP00000112955, ENSMUSP00000113753, ENSMUSP00000113698
RefSeq: NP_001156920.1, NP_001156921.1, NP_001156919.1, NP_001156922.1, NP_001156925.1, NP_038959.2, NP_001156923.1
Others
UniRef100: UniRef100_Q9ESN9, UniRef100_E9Q6B6, UniRef100_E9Q6E0, UniRef100_Q6P1F1, UniRef100_K3W4S4
UniRef90: UniRef90_Q9ESN9, UniRef90_Q9ESN9-6
UniRef50: UniRef50_Q9ESN9-6, UniRef50_Q9ESN9
UniGene: Mm.43081
CCDS: CCDS50024.1, CCDS50025.1, CCDS50026.1, CCDS37498.1, CCDS50029.1

全选

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研究热度

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