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30942 Hnf4g

30942

Hnf4g

hepatocyte nuclear factor 4, gamma

protein-coding

Mus musculus

基因描述

Type Description
Definition hepatocyte nuclear factor 4, gamma

研究结论

Date Results Publications
2020-07-04 11:49:00 Genetic inactivation of Hnf4a and its paralog Hnf4g revealed that HNF4 factors are redundantly required for fetal maturation. 31345929
2019-06-15 12:28:00 HNF4A acts redundantly with an intestine-restricted HNF4 paralog, HNF4G, to activate enhancer chromatin and upregulate the majority of transcripts in the differentiated epithelium; cells fail to differentiate on double knockout of both HNF4 paralogs. Furthermore, we show that SMAD4 and HNF4 function via a reinforcing feed-forward loop. 30988513
2015-10-10 10:17:00 the loss of HNF-4gamma improves glucose homeostasis through a modulation of the enteroendocrine cell lineage. 25829452
2010-01-21 00:00:00 HNF4g has a role in energy expenditure, locomotor activity during night time, and higher body weight 16945327

名称对应

Type IDs
Synonymous NR2A2
Gene
UniProtKB-ID: HNF4G_MOUSE, Q3UP48_MOUSE, Q059V1_MOUSE, E9QPS1_MOUSE
UniprotKB: Q9WUU6, Q3UP48, Q059V1, E9QPS1
UniParc: UPI00005AC239, UPI0000F22241, UPI0000028F27, UPI000016383B
EMBL: AC157926, AC157764, BC125519, AK143816, AJ242626, AC107454, AC170259
Ensembl: ENSMUSG00000017688
KO: mmu:30942
Nucleutide sequences
EMBL-CDS: CAB43724.1, BAE25549.1, AAI25520.1
Ensembl_TRS: ENSMUST00000108393, ENSMUST00000108394
Protein sequencees
Ensembl_PRO: ENSMUSP00000104030, ENSMUSP00000104031
RefSeq: XP_006530135.1, NP_038948.1
Others
UniRef100: UniRef100_Q9WUU6, UniRef100_Q059V1, UniRef100_Q3UP48
UniRef90: UniRef90_Q14541
UniRef50: UniRef50_Q14541
UniGene: Mm.330897

全选

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研究热度

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