| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 21 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 11:16:00 | USP21 interacts with, deubiquitinates and stabilizes Nanog, and therefore maintains the protein level of Nanog in mouse embryonic stem cells to maintain stemness. | 27886188 |
| 2017-08-12 11:47:00 | USP21 recruits and stabilises Gli1 at the centrosome. | 27621083 |
| 2016-01-02 10:07:00 | Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation | 25680095 |
| 2014-04-19 10:11:00 | Overexpression of USP21 inhibited RNA virus-induced RIG-I polyubiquitination and RIG-I-mediated interferon signaling, while USP21 deletion resulted in elevated RIG-I polyubiquitination, IRF3 phosphorylation, IFN production, and antiviral responses. | 24493797 |
| 2010-02-01 11:35:00 | USP21 plays an important role in the down-regulation of TNFalpha-induced NF-kappaB activation through deubiquitinating RIP1. | 19910467 |
| Type | IDs |
|---|---|
| Synonymous | ESTM28, Usp16, Usp23, W53272 |
| Gene |
UniProtKB-ID:
UBP21_MOUSE,
E9PUE2_MOUSE
UniprotKB:
Q9QZL6,
E9PUE2
UniParc:
UPI0000F220FE,
UPI00000019B5
EMBL:
AK011148,
AC084821,
BC021903,
AF177759
Ensembl:
ENSMUSG00000053483
KO:
mmu:30941
|
| Nucleutide sequences |
EMBL-CDS:
BAB27431.1,
AAH21903.1,
AAD54322.1
Ensembl_TRS:
ENSMUST00000111305,
ENSMUST00000065941
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064002,
ENSMUSP00000106936
RefSeq:
NP_038947.2
|
| Others |
UniRef100:
UniRef100_E9PUE2,
UniRef100_Q9QZL6
UniRef90:
UniRef90_Q9QZL6
UniRef50:
UniRef50_Q9QZL6
UniGene:
Mm.27510
CCDS:
CCDS35774.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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