Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

A mitochondrial protein compendium elucidates complex I disease biology.

Cell     David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha

Functional and genetic studies demonstrate that mutation in the COX15 gene can cause Leigh syndrome.

J. Med. Genet.     C E Oquendo , H Antonicka , E A Shoubridge , W Reardon , G K Brown

Identification of candidate disease genes by EST alignments, synteny, and expression and verification of Ensembl genes on rat chromosome 1q43-54.

Genome Res.     Ursula Vitt , Darryl Gietzen , Kristian Stevens , Jim Wingrove , Shanya Becha , Sean Bulloch , John Burrill , Narinder Chawla , Jennifer Chien , Matthew Crawford , Craig Ison , Liam Kearney , Mary Kwong , Joe Park , Jennifer Policky , Mark Weiler , Renee White , Yuming Xu , Sue Daniels , Howard Jacob , Michael I Jensen-Seaman , Jozef Lazar , Laura Stuve , Jeanette Schmidt

Proteomic analysis of the mouse liver mitochondrial inner membrane.

J Biol Chem     Sandrine Da Cruz , Ioannis Xenarios , James Langridge , Francis Vilbois , Phillipe A Parone , Jean-Claude Martinou

Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy.

Am J Hum Genet     Hana Antonicka , Andre Mattman , Christopher G Carlson , D Moira Glerum , Kristen C Hoffbuhr , Scot C Leary , Nancy G Kennaway , Eric A Shoubridge

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Proc. Natl. Acad. Sci. U.S.A.     Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team

Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.

Genomics     V Petruzzella , V Tiranti , P Fernandez , P Ianna , R Carrozzo , M Zeviani

Isoforms of mammalian cytochrome c oxidase: correlation with human cytochrome c oxidase deficiency.

Pediatr. Res.     N G Kennaway , R D Carrero-Valenzuela , G Ewart , V K Balan , R Lightowlers , Y Z Zhang , B R Powell , R A Capaldi , N R Buist