| Type | Description |
|---|---|
| Definition | ubiquitin conjugating enzyme E2 K |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:18:00 | Expression of UBE2K's transcript has been shown to be dysregulated in the brain of individuals with a psychiatric illness and in the blood transcript expression was associated with positive symptom severity in schizophrenia. | 30901725 |
| 2019-10-12 11:16:00 | The data indicate that active site gate opening and closing rates for E2-25K are precisely balanced. | 29725124 |
| 2019-05-18 10:19:00 | Crystal structure of the Ube2K/E2-25K and K48-linked diubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis. | 30336976 |
| 2019-04-06 12:42:00 | Hip2 works as a regulator in UV-induced cell cycle arrest and re-entry. | 30264212 |
| 2016-09-24 10:51:00 | The crystal structure of a Ube2K~ubiquitin conjugate has been described, and it was shown that even though it is monomeric, Ube2K can synthesize Lys48-linked ubiquitin chains. | 26592444 |
| Type | IDs |
|---|---|
| Synonymous | E2-25K, HIP2, HYPG, LIG, UBC1 |
| Gene |
UniProtKB-ID:
UBE2K_HUMAN,
B3KSH4_HUMAN,
B4DIZ2_HUMAN
UniprotKB:
P61086,
B3KSH4,
B4DIZ2
UniParc:
UPI00001F2A9F,
UPI00017A7324,
UPI0000003FF1,
UPI00005A04E4,
UPI0000073AFA
EMBL:
AK315524,
BC022804,
AC105287,
CH471069,
AK295846,
U58522,
AC108471,
BC050600,
BX339118,
AB022435,
AK093533,
AK291454,
AB022436
Ensembl:
ENSG00000078140
KO:
hsa:3093
|
| Nucleutide sequences |
EMBL-CDS:
BAF84143.1,
AAH50600.1,
AAH22804.1,
BAG37905.1,
EAW92948.1,
BAA78556.1,
BAA78555.1,
AAC50633.1,
EAW92947.1,
EAW92946.1,
BAG52736.1,
BAG58654.1
Gene_ORFName:
hCG_38552
Ensembl_TRS:
ENST00000503368,
ENST00000445950,
ENST00000261427
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000421203,
ENSP00000261427,
ENSP00000390483
RefSeq:
NP_001299575.1,
NP_005330.1,
NP_001104582.1,
NP_001299577.1,
NP_001299576.1,
NP_001104583.1
|
| Others |
UniRef100:
UniRef100_P61086,
UniRef100_A0A0J9YUI1,
UniRef100_B3KSH4
UniRef90:
UniRef90_B3KSH4,
UniRef90_P61086,
UniRef90_A0A0J9YUI1
UniRef50:
UniRef50_B3KSH4,
UniRef50_A0A665WHK0,
UniRef50_P61086
UniGene:
Hs.50308
CCDS:
CCDS33976.1,
CCDS47043.1,
CCDS47044.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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