| Type | Description |
|---|---|
| Definition | vitamin K epoxide reductase complex, subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | The VKORC1 ER-luminal loop mutation (Leu76Pro) leads to a significant resistance to warfarin in black rats (Rattus rattus). | 33771253 |
| 2020-12-26 13:12:00 | A VKORC1-based SNP survey of anticoagulant rodenticide resistance in the house mouse, Norway rat and roof rat in the USA. | 32687688 |
| 2020-02-22 10:29:00 | These studies evaluated the association between vitamin K dietary deficiency and mutations in the VKORC1 enzyme. | 31484376 |
| 2019-11-09 11:00:00 | Mutation in VKORC1 associated with a limited vitamin K intake is thus a major risk for cardiovascular disease. Our model is the first non-invasive rat model that shows spontaneous medial calcifications and would be useful for studying physiological function of vitamin K. | 30214074 |
| 2018-09-08 10:41:00 | This study demonstrated that elevated CYP450 oxidative metabolism leading to accelerated difenacoum detoxification is involved in the Berkshire phenotype of L120Q mutation in Vkorc1. | 29155484 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
VKOR1_RAT,
B2GUU6_RAT
UniprotKB:
Q6TEK4,
B2GUU6
UniParc:
UPI00001C7481
EMBL:
BC166413,
LC218159,
LC218153,
LC218160,
AY423047,
LC218154,
LC218165,
LC218161,
LC218155,
CH473956,
LC218163
Ensembl:
ENSRNOG00000050828
KO:
rno:309004
|
| Nucleutide sequences |
EMBL-CDS:
AAR82917.1,
EDM17218.1,
BAX00328.1,
BAX00324.1,
BAX00319.1,
BAX00325.1,
AAI66413.1,
BAX00320.1,
BAX00318.1,
BAX00330.1,
BAX00326.1
Gene_ORFName:
rCG_39714
Ensembl_TRS:
ENSRNOT00000073596
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000063977
RefSeq:
NP_976080.1
|
| Others |
UniRef100:
UniRef100_Q6TEK4
UniRef90:
UniRef90_Q6TEK4
UniRef50:
UniRef50_Q6TEK4
UniGene:
Rn.97942
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员