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3090 HIC1

3090

HIC1

HIC ZBTB transcriptional repressor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition HIC ZBTB transcriptional repressor 1

研究结论

Date Results Publications
2021-04-17 13:38:00 Detection of aberrant methylation of HOXA9 and HIC1 through multiplex MethyLight assay in serum DNA for the early detection of epithelial ovarian cancer. 32191343
2020-07-11 11:39:00 Low HIC1 expression is associated with bladder cancer progression. 30417565
2020-05-23 10:58:00 IL-6 present in the tumor microenvironment downregulates the tumor suppressor HIC1 in breast cancer cells. 31795965
2020-02-29 10:39:00 HIC1 expression was downregulated in lung tumor tissues. Loss of HIC1 expression increased proliferation and migration. DNA repair pathway was associated with loss of HIC1. 30312658
2019-09-21 11:56:00 the chemokine (C-X-C motif) ligand 14 (CXCL14) secreted by HIC1-deleted Breast cancer cells bound to its cognate receptor GPR85 on mammary fibroblasts in the microenvironment and was responsible for activating these fibroblasts via the ERK1/2, Akt, and neddylation pathways. 30204129

名称对应

Type IDs
Synonymous ZBTB29, ZNF901, hic-1
Gene
UniProtKB-ID: HIC1_HUMAN, A0PJI1_HUMAN
UniprotKB: Q14526, A0PJI1
UniParc: UPI0000140F7F, UPI0000D49C8D, UPI00004EC06B
EMBL: L41919, CH471108, AC090617, BC030208
Ensembl: ENSG00000177374
KO: hsa:3090
Nucleutide sequences
EMBL-CDS: EAW90563.1, AAD09201.1, EAW90562.1, AAH30208.1
Ensembl_TRS: ENST00000322941, ENST00000399849, ENST00000619757
Protein sequencees
Ensembl_PRO: ENSP00000382742, ENSP00000314080, ENSP00000477858
RefSeq: NP_006488.2, NP_001091672.1
Others
UniRef100: UniRef100_A0PJI1, UniRef100_Q14526
UniRef90: UniRef90_Q14526
UniRef50: UniRef50_Q14526
UniGene: Hs.72956, Hs.695682
CCDS: CCDS42230.1, CCDS42229.1

全选

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