Itgal - integrin subunit alpha L-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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308995 Itgal

基因描述

Type	Description
Definition	integrin subunit alpha L

研究结论

Date	Results	Publications
2020-04-25 12:30:00	Prenatal alcohol exposure (PAE) creates a risk for developing peripheral neuropathies, and LFA-1 may be a novel therapeutic target for controlling dysregulated neuroimmune actions as a consequence of PAE.	30961664
2011-03-12 10:21:00	Downregulated expression of CD11a in an experimental model of depression could be an important mechanisms to induce impaired immune responses in experimental and clinical depression.	20516718

名称对应

Type	IDs
Synonymous	LFA-1
Gene	UniProtKB-ID: Q3T1L6_RAT, F1LP44_RAT UniprotKB: Q3T1L6, F1LP44 UniParc: UPI000017EA8D, UPI00005B619E EMBL: AABR07005779, BC101849 Ensembl: ENSRNOG00000017980 KO: rno:308995
Nucleutide sequences	EMBL-CDS: AAI01850.1 Ensembl_TRS: ENSRNOT00000024404
Protein sequencees	Ensembl_PRO: ENSRNOP00000024404 RefSeq: XP_006230331.1, NP_001029170.1
Others	UniRef100: UniRef100_F1LP44, UniRef100_Q3T1L6 UniRef90: UniRef90_F1LP44 UniRef50: UniRef50_P20701 UniGene: Rn.14655

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
30961664	Targeting the Î²2-integrin LFA-1, reduces adverse neuroimmune actions in neuropathic susceptibility caused by prenatal alcohol exposure. Acta Neuropathol Commun Joshua J Sanchez , Jacob E Sanchez , Shahani Noor , Chaselyn D Ruffaner-Hanson , Suzy Davies , Carston R Wagner , Lauren L Jantzie , Nikolaos Mellios , Daniel D Savage , Erin D Milligan	2019-04-08	-
23981064	Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines. Immunology Lawton L Roberts , Cory M Robinson	2014-01-01	CD209, ICAM1, ITGAL, ITGAM, ITGAX, ITGB1, ITGB2, CD1B, CD80, CD86, CD40
23793062	The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. Nat Immunol Yinming Liang , Margot Cucchetti , Romain Roncagalli , Tadashi Yokosuka , AurÃ©lie Malzac , Elodie Bertosio , Jean Imbert , Isaac J Nijman , Miloslav Suchanek , Takashi Saito , Christoph WÃ¼lfing , Bernard Malissen , Marie Malissen	2013-08-01	-
20458337	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. Sonja I Buschow , Bas W M van Balkom , Marian Aalberts , Albert J R Heck , Marca Wauben , Willem Stoorvogel	2010-05-11	-
20516718	Forced swimming test decreases chemotactic responsiveness and expression of CD11a in rat monocytes. Neuroimmunomodulation Francisco BriceÃ±o , JosÃ© Luis Arcaya , Edgardo Carrizo , Jaimar RincÃ³n , JesÃºs Mosquera	2010-01-01	Itgal, ITGAL
19946888	Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins	2010-01-01	MED6, PDCD6IP, MED16, PIGK, DNAJB6, FARSB, DNM1L, ABCF2, HUWE1, ARPC3, ACTR3, ACTR2, RAD50, PREB, ACTR1B, LRPPRC, TRAP1, BCAP31, PLXNC1, LPCAT3, TNK2, PSME3, MPHOSPH9, FLOT1, DDX39A, AK6, ADAM10, PLIN3, CALCOCO2, CDK9, ABCC4, ZMPSTE24, AKAP8, BET1, MARCH6, KATNB1, ADAR, EMC8, BTN3A3, ATP8A1, NDC80, CDIPT, PGRMC2, TUBGCP3, ECI2, COG5, SLC25A17, LRRC41, SYNCRIP, MYBBP1A, DDX17, CHERP, HYOU1, IPO7, NOP56, ARL6IP5, HTATIP2, AGPAT1, ARFGEF2, RABAC1, SLU7, PRPF8, PAICS, CENPE, PMVK, KHDRBS1, CELF1, GNA13, CFL1, MGEA5, YME1L1, STAG2, CTSC, GIPC1, HBS1L, TUBGCP2, PGRMC1, MAN1A2, PNPLA6, MAGED2, ADCY3, EHD1, TOMM34, ERP29, YWHAQ, ASCC3, GCN1, IMMT, ILVBL, SLC27A4, SLC27A3, KIF2C, GLIPR1, CPSF6, DDX52, WWP2, CNTRL, CHD4, KRR1
19234460	A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. Nat Med Nikolay L Malinin , Li Zhang , Jeongsuk Choi , Alieta Ciocea , Olga Razorenova , Yan-Qing Ma , Eugene A Podrez , Michael Tosi , Donald P Lennon , Arnold I Caplan , Susan B Shurin , Edward F Plow , Tatiana V Byzova	2009-03-01	-
19029120	Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunits. J Biol Chem Ardcharaporn Vararattanavech , Xin Lin , Jaume Torres , Suet-Mien Tan	2009-01-30	-
17543136	The integrins. Genome Biol. Yoshikazu Takada , Xiaojing Ye , Scott Simon	2007-01-01	Itga6, Itga2, Itgb1, Itgam, Itga1, Itgb7, Itgb4, Itgb5, Itgb3, Itgav, Itgal, Itgb2, Itga10, Itgb6, Itga4, Itga5, Itga11, Itga3, Itgb8, Itga8, Itgax, Itgad, Itga2b, Itga7, Itgae, mew, if, Itgbn, scb, mys
15210787	Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes. J. Immunol. Huaizhu Wu , John R Rodgers , Xiao-Yuan Dai Perrard , Jerry L Perrard , Joseph E Prince , Yasunori Abe , Beckley K Davis , Greg Dietsch , C Wayne Smith , Christie M Ballantyne	2004-07-01	-

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