| Type | Description |
|---|---|
| Definition | cancer/testis antigen 2 |
| Date | Results | Publications |
|---|---|---|
| 2015-01-17 12:37:00 | The tumor suppressor function of LSAMP is most likely exerted by reducing the proliferation rate of the tumor cells, possibly by indirectly upregulating one or more of the genes HES1, CTAG2 or KLF10. | 24885297 |
| 2012-09-01 11:22:00 | NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine | 22384167 |
| 2011-04-30 10:35:00 | LAGE-1a and NY-ESO-1 homology cannot be easily exploited in an anti-NY-ESO-1 vaccine given the low frequency of protein expression detected by IHC or serum analysis. | 21247062 |
| 2011-01-29 10:36:00 | Spontaneous LAGE-1-specific CD4-positive T cells isolated from patients with advanced LAGE-1-positive/NY-ESO-1-positive melanoma are directed against three promiscuous and immunodominant epitopes. | 21131422 |
| 2010-01-21 00:00:00 | MAGEC1/CT7, MAGEA3/6 and LAGE-1 are good candidates for immunotherapy, since together they cover 85% of the multiple myeloma cases. | 18237105 |
| Type | IDs |
|---|---|
| Synonymous | CAMEL, CT2, CT6.2, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE2B |
| Gene |
UniProtKB-ID:
CTAG2_HUMAN
UniprotKB:
O75638
UniParc:
UPI000006D049,
UPI000002A779
EMBL:
AJ223093,
AY679089,
AJ012834,
BC113998,
AJ223041,
AJ223040,
AF277315,
AY679088,
AJ012835,
BC002833,
AC244107,
BC128045
Ensembl:
ENSG00000126890
KO:
hsa:30848
|
| Nucleutide sequences |
EMBL-CDS:
CAA10196.1,
AAV98584.1,
CAA11117.1,
CAA11116.1,
CAA11044.1,
AAI28046.1,
CAA10194.1,
AAI13999.1,
AAV98585.1,
AAL27015.1,
AAH02833.1,
CAA11043.1
Ensembl_TRS:
ENST00000247306,
ENST00000369585
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358598,
ENSP00000247306
RefSeq:
NP_758965.2,
NP_066274.2
|
| Others |
UniRef100:
UniRef100_O75638
UniRef90:
UniRef90_O75638
UniRef50:
UniRef50_P78358
UniGene:
Hs.87225,
Hs.713312
CCDS:
CCDS35455.1,
CCDS14759.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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