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30846 EHD2

30846

EHD2

EH domain containing 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition EH domain containing 2

研究结论

Date Results Publications
2020-08-15 19:08:00 EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. 32170013
2020-03-14 12:22:00 EHD2-controlled caveolar dynamics orchestrates the activity and regulation of eNOS/nitric oxide and Ca2+ channel localization at the plasma membrane. 31600286
2020-01-04 11:38:00 EHD2 can promote the proliferation, invasion, and migration and inhibit the apoptosis of clear cell renal cell carcinoma (ccRCC) cells, so EHD2 interference can significantly inhibit the development of ccRCC, and EHD2 can potentially serve as a molecular target for the clinical treatment of ccRCC. 30995867
2019-09-28 11:41:00 findings therefore define EHD2 as a central player in mechanotransduction connecting the disassembly of the caveolae reservoir with the regulation of gene transcription under mechanical stress. 30348749
2019-09-14 11:17:00 EHD2 overexpression in human adipocytes increased the lipolytic signaling and suppressed the activity of transcription factor PPARgamma. Overall, these data suggest that EHD2 plays a key role for adipocyte function. 30811273

名称对应

Type IDs
Synonymous PAST2
Gene
UniProtKB-ID: EHD2_HUMAN, A0A024R0S6_HUMAN
UniprotKB: Q9NZN4, A0A024R0S6
UniParc: UPI00017A7684, UPI0000071B66
EMBL: AK298067, BC014445, AK315548, AC010519, AF181263, CH471126, AC008745, AF454952
Ensembl: ENSG00000024422
KO: hsa:30846
Nucleutide sequences
EMBL-CDS: BAG60358.1, AAL51078.1, BAG37926.1, AAH14445.1, EAW57505.1, AAF40470.1, EAW57506.1
Gene_ORFName: hCG_20547
Ensembl_TRS: ENST00000263277, ENST00000538399
Protein sequencees
Ensembl_PRO: ENSP00000439036, ENSP00000263277
RefSeq: NP_055416.2
Others
UniRef100: UniRef100_Q9NZN4
UniRef90: UniRef90_Q8BH64
UniRef50: UniRef50_Q8BH64
UniGene: Hs.744963
CCDS: CCDS12704.1

全选

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