| Type | Description |
|---|---|
| Definition | EH domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-17 10:47:00 | Data provide evidence that EHD3 might undergo its tumor suppressor functions at least in part through promoting the sorting of activated EGFR to the lysosomal degradative compartment and spatio-temporal regulation of EGFR signaling via ERK and AKT. | 27811356 |
| 2016-11-12 10:51:00 | the residues Ala-519/Asp-520 of EHD1 and Asn-519/Glu-520 of EHD3 as defining the selectivity of these two paralogs for NPF-containing binding partners | 27189942 |
| 2015-02-28 13:09:00 | The EHD3 gene may be associated with the endophenotype of cognitive function in major depressive disorder patients. | 24997812 |
| 2014-11-22 11:14:00 | 3 SNPs present in the EHD3 gene, of which rs619002 and rs644926 were exclusively associated with female major depressive disorder | 24607927 |
| 2014-05-31 11:09:00 | demonstrate Ehd3 growth inhibitory functions in glioma cells in vivo. We suggest that Ehd3 functions as a tumor suppressor gene and loss of its expression is a very common event in gliomas | 24306026 |
| Type | IDs |
|---|---|
| Synonymous | PAST3 |
| Gene |
UniProtKB-ID:
EHD3_HUMAN
UniprotKB:
Q9NZN3
UniParc:
UPI0000140D07,
UPI00017A6F8B
EMBL:
CH471053,
AL121657,
AK316006,
AK294222,
AF181264,
AF214736
Ensembl:
ENSG00000013016
KO:
hsa:30845
|
| Nucleutide sequences |
EMBL-CDS:
BAH14377.1,
AAF40471.1,
EAX00480.1,
AAF32285.1,
EAX00481.1,
BAG57526.1
Ensembl_TRS:
ENST00000322054
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327116
RefSeq:
XP_011531108.1,
NP_055415.1
|
| Others |
UniRef100:
UniRef100_Q9NZN3
UniRef90:
UniRef90_Q9NZN3
UniRef50:
UniRef50_Q9NZN3
UniGene:
Hs.368808
CCDS:
CCDS1774.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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