| Type | Description |
|---|---|
| Definition | HGF activator |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:50:00 | Hypermethylation around the promoter region contributed to the decreased expression of HGFAC. HGFAC may be a useful and predictive biomarker for the prognosis of liver cancer patients. | 30635948 |
| 2015-09-05 11:34:00 | Based upon ethnicity-stratified single-variant association analysis and trans-ethnic meta-analysis of 6201 participants of the Multi-Ethnic Study of Atherosclerosis, discovered 5 common and low-frequency variants: HGF missense polymorphism rs5745687 (p.E299K) and 4 variants (rs16844364, rs4690098, rs114303452, rs3748034) within or in proximity to HGFAC.[Meta-analysis] | 25998175 |
| 2010-06-30 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20424473 |
| 2010-01-21 00:00:00 | Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer. | 18422749 |
| 2010-01-21 00:00:00 | the HGF-activator has a role in multiple myeloma cells' catalysis of hepatocyte growth factor (HGF) activation | 15172968 |
| Type | IDs |
|---|---|
| Synonymous | HGFA |
| Gene |
UniProtKB-ID:
HGFA_HUMAN,
D6RAR4_HUMAN
UniprotKB:
Q04756,
D6RAR4
UniParc:
UPI0001D3B0DD,
UPI0000000826
EMBL:
CH471131,
AL590235,
BC112190,
D50030,
D14012,
BC112192
Ensembl:
ENSG00000109758
KO:
hsa:3083
|
| Nucleutide sequences |
EMBL-CDS:
BAA03113.1,
EAW82464.1,
AAI12193.1,
AAI12191.1,
BAA74450.1
Ensembl_TRS:
ENST00000382774,
ENST00000511533
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000372224,
ENSP00000421801
RefSeq:
NP_001519.1,
NP_001284368.1
|
| Others |
UniRef100:
UniRef100_Q04756,
UniRef100_D6RAR4
UniRef90:
UniRef90_Q04756,
UniRef90_A0A2I3S7G2
UniRef50:
UniRef50_Q04756
UniGene:
Hs.104
CCDS:
CCDS3369.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31536960 |
iScience Mohamed Taha Moutaoufik , Ramy Malty , Shahreen Amin , Qingzhou Zhang , Sadhna Phanse , Alla Gagarinova , Mara Zilocchi , Larissa Hoell , Zoran Minic , Maria Gagarinova , Hiroyuki Aoki , Jocelyn Stockwell , Matthew Jessulat , Florian Goebels , Kirsten Broderick , Nichollas E Scott , James Vlasblom , Gabriel Musso , Bhanu Prasad , Eleonora Lamantea , Barbara Garavaglia , Alex Rajput , Kei Murayama , Yasushi Okazaki , Leonard J Foster , Gary D Bader , Francisco S Cayabyab , Mohan Babu |
2019-09-27 | - |
| 30635948 |
J. Cell. Biochem. Li Yin , Yudong Mu , Yingzi Lin , Qianfeng Xia |
2019-06-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25998175 |
Ann. Hum. Genet. Nicholas B Larson , Cecilia Berardi , Paul A Decker , Christina L Wassel , Phillip S Kirsch , James S Pankow , Michele M Sale , Mariza de Andrade , Hugues Sicotte , Weihong Tang , Naomi Q Hanson , Michael Y Tsai , Kent D Taylor , Suzette J Bielinski |
2015-07-01 | - |
| 23969696 |
Circulation Maria Sabater-Lleal , Jie Huang , Daniel Chasman , Silvia Naitza , Abbas Dehghan , Andrew D Johnson , Alexander Teumer , Alex P Reiner , Lasse Folkersen , Saonli Basu , Alicja R Rudnicka , Stella Trompet , Anders Mälarstig , Jens Baumert , Joshua C Bis , Xiuqing Guo , Jouke J Hottenga , So-Youn Shin , Lorna M Lopez , Jari Lahti , Toshiko Tanaka , Lisa R Yanek , Tiphaine Oudot-Mellakh , James F Wilson , Pau Navarro , Jennifer E Huffman , Tatijana Zemunik , Susan Redline , Reena Mehra , Drazen Pulanic , Igor Rudan , Alan F Wright , Ivana Kolcic , Ozren Polasek , Sarah H Wild , Harry Campbell , J David Curb , Robert Wallace , Simin Liu , Charles B Eaton , Diane M Becker , Lewis C Becker , Stefania Bandinelli , Katri Räikkönen , Elisabeth Widen , Aarno Palotie , Myriam Fornage , David Green , Myron Gross , Gail Davies , Sarah E Harris , David C Liewald , John M Starr , Frances M K Williams , Peter J Grant , Timothy D Spector , Rona J Strawbridge , Angela Silveira , Bengt Sennblad , Fernando Rivadeneira , Andre G Uitterlinden , Oscar H Franco , Albert Hofman , Jenny van Dongen , Gonneke Willemsen , Dorret I Boomsma , Jie Yao , Nancy Swords Jenny , Talin Haritunians , Barbara McKnight , Thomas Lumley , Kent D Taylor , Jerome I Rotter , Bruce M Psaty , Annette Peters , Christian Gieger , Thomas Illig , Anne Grotevendt , Georg Homuth , Henry Völzke , Thomas Kocher , Anuj Goel , Maria Grazia Franzosi , Udo Seedorf , Robert Clarke , Maristella Steri , Kirill V Tarasov , Serena Sanna , David Schlessinger , David J Stott , Naveed Sattar , Brendan M Buckley , Ann Rumley , Gordon D Lowe , Wendy L McArdle , Ming-Huei Chen , Geoffrey H Tofler , Jaejoon Song , Eric Boerwinkle , Aaron R Folsom , Lynda M Rose , Anders Franco-Cereceda , Martina Teichert , M Arfan Ikram , Thomas H Mosley , Steve Bevan , Martin Dichgans , Peter M Rothwell , Cathie L M Sudlow , Jemma C Hopewell , John C Chambers , Danish Saleheen , Jaspal S Kooner , John Danesh , Christopher P Nelson , Jeanette Erdmann , Muredach P Reilly , Sekar Kathiresan , Heribert Schunkert , Pierre-Emmanuel Morange , Luigi Ferrucci , Johan G Eriksson , David Jacobs , Ian J Deary , Nicole Soranzo , Jacqueline C M Witteman , Eco J C de Geus , Russell P Tracy , Caroline Hayward , Wolfgang Koenig , Francesco Cucca , J Wouter Jukema , Per Eriksson , Sudha Seshadri , Hugh S Markus , Hugh Watkins , Nilesh J Samani , VTE Consortium , STROKE Consortium , Wellcome Trust Case Control Consortium 2 (WTCCC2) , C4D Consortium , CARDIoGRAM Consortium , Henri Wallaschofski , Nicholas L Smith , David Tregouet , Paul M Ridker , Weihong Tang , David P Strachan , Anders Hamsten , Christopher J O'Donnell |
2013-09-17 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20424473 |
Nephron Clin Pract Keitaro Yokoyama , Mitsuyoshi Urashima , Ichiro Ohkido , Takashi Kono , Toyohiko Yoshida , Masaaki Muramatsu , Tianhua Niu , Tatsuo Hosoya |
2010-01-01 |
SCAMP2,
CALCRL,
B3GNT3,
SLC27A4,
SLC7A9,
CHI3L1,
CMA1,
HBEGF,
EGF,
EGFR,
SERPINB1,
ADGRE1,
ADGRG3,
FGF1,
FGF9,
FGF10,
FOLR1,
FOLR2,
SLC16A8,
GC,
OSTF1,
GFRA1,
GHRHR,
GIP,
GIPR,
KCNMB3P1,
GNRH1,
GPR37,
MLNR,
GPR39,
GRK4,
GRK6,
HGF,
HGFAC,
AQP8,
BMP8A,
IL2,
IL2RA,
IL2RB,
IL3,
IL4,
IL4R,
IL7R,
IL9R,
AQP1,
IL10,
IL10RA,
IL10RB,
IL12RB1,
IL12RB2,
IL15RA,
AQP9,
KCNE1,
KCNJ1,
KCNJ4,
KCNJ6,
KCNJ14,
KCNMA1,
KCNMB1,
KCNQ1,
LHCGR,
LTBP2,
MET,
NPHP1,
NPHS1,
NTRK1,
NTSR1,
OPRM1,
P2RX7,
PDGFRA,
PDGFRB,
GPRC5B,
PHEX,
POMC,
GPRC5D,
PRL,
PTH1R,
RYR1,
RYR2,
RYR3,
SCNN1A,
SCNN1B,
BMP2,
SLC1A4,
SLC1A6,
SLC1A7,
SLC2A1,
SLC2A2,
SLC2A3,
SLC4A1,
SLC4A2,
SLC5A1,
SLC6A2,
SLC6A6,
SLC6A7,
SLC6A11,
SLC6A12,
SLC6A13,
SLC7A2
|
| 19456860 |
FEBS J. Makiko Kawaguchi , Hiroshi Orikawa , Takashi Baba , Tsuyoshi Fukushima , Hiroaki Kataoka |
2009-07-01 |
HGFAC,
MST1
|
| 18691255 |
Eur. J. Haematol. K F Wader , U M Fagerli , R U Holt , B Stordal , M Børset , A Sundan , A Waage |
2008-11-01 |
HGF,
HGFAC
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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