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30812 SOX8

30812

SOX8

SRY-box 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition SRY-box 8

研究结论

Date Results Publications
2021-01-16 15:59:00 Variation analysis of SOX8 gene in Chinese men with non-obstructive azoospermia or oligozoospermia. 32048324
2020-05-30 13:48:00 High SOX8 expression is associated with progression of triple-negative breast cancer. 30810729
2020-05-09 13:04:00 These observations demonstrate that Sox8 is a novel player essential for the differentiation of M cells and antigen-specific IgA response in the gut. 30877171
2020-01-11 12:14:00 A transactivation domain in the middle of the proteins (TAM) synergizes with a C-terminal one (TAC). TAM comprises amphipathic alpha-helices predicted to form a protein-binding pocket and overlapping with minimal transactivation motifs (9-aa-TAD). One 9-aa-TAD sequence includes an evolutionarily conserved and functionally required EPhi[D/E]QYPhi motif. 31194875
2019-07-13 10:51:00 SOX8 is over-expressed in patients with high T stage, which affects the outcome of prognosis in CRC patients. High expression of SOX8 usually has a poor independent prognostic factor for CRC. 31277140

名称对应

Type IDs
Gene
UniProtKB-ID: SOX8_HUMAN
UniprotKB: P57073
UniParc: UPI00000015FB
EMBL: AF164104, BC031797, Z99757, AF226675, AE006465
Ensembl: ENSG00000005513
KO: hsa:30812
Nucleutide sequences
EMBL-CDS: CAB75612.1, AAF35886.1, AAH31797.1, AAK61260.1, AAF37424.1
Ensembl_TRS: ENST00000293894
Protein sequencees
Ensembl_PRO: ENSP00000293894
RefSeq: NP_055402.2
Others
UniRef100: UniRef100_P57073
UniRef90: UniRef90_P57073
UniRef50: UniRef50_P57073
UniGene: Hs.243678
CCDS: CCDS10428.1

全选

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