| Type | Description |
|---|---|
| Definition | hormonally up-regulated Neu-associated kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:15:00 | HUNK phosphorylates EGFR to regulate breast cancer metastasis. | 31597954 |
| 2020-04-11 10:16:00 | Rubicon as a novel substrate of HUNK. | 31752345 |
| 2017-05-27 11:07:00 | Recent work demonstrates a role for Hunk in HER2(+)/ErbB2(+) breast cancer progression, including drug resistance to HER2/ErbB2 inhibitors, with Hunk potentially acting downstream of HER2/ErbB2 and the PI3K/Akt pathway. [review] | 28189783 |
| 2015-10-03 11:21:00 | Our findings indicate that therapeutically targeting HUNK is a potential strategy for overcoming resistance and that resistant breast cancer cells maintain HUNK expression to drive tumorigenesis | 25515931 |
| 2011-04-30 10:35:00 | Hunk is required for HER2/neu-induced mammary tumorigenesis | 21393859 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HUNK_HUMAN
UniprotKB:
P57058
UniParc:
UPI0000035B66
EMBL:
AJ271722
Ensembl:
ENSG00000142149
KO:
hsa:30811
|
| Nucleutide sequences |
EMBL-CDS:
CAB71146.1
Ensembl_TRS:
ENST00000270112
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000270112
RefSeq:
XP_011527839.1,
NP_055401.1
|
| Others |
UniRef100:
UniRef100_P57058
UniRef90:
UniRef90_P57058
UniRef50:
UniRef50_P57058
UniGene:
Hs.109437
CCDS:
CCDS13610.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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