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30805 Slc22a4

30805

Slc22a4

solute carrier family 22 (organic cation transporter), member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 22 (organic cation transporter), member 4

研究结论

Date Results Publications
2020-04-18 11:00:00 There was a significant upregulation of mOctn1 and mOctn2 mRNA by qRT-PCR in mdx quadriceps and of mOctn2 and mOctn3 mRNA in mdx heart 32070725
2018-08-18 10:44:00 OCTN1 negatively regulated the induction of inflammatory cytokine IL-1beta 28688036
2018-07-07 10:13:00 Dysfunction of intestinal OCTN1 in mouse model of chronic kidney disease (CKD) impaired the OCTN1-ergothioneine axis, an adaptive antioxidant system, and that decreased antioxidant ergothioneine levels may contribute to CKD progression in a PDZK1-dependent manner. 28754554
2016-03-26 10:31:00 OCTN1 is functionally expressed on activated intestinal macrophages, and ergothioneine uptake into these immune cells could contribute at least in part to the altered disposition of ergothioneine in intestinal inflammation. 26003890
2015-04-04 13:00:00 The bile acids that accumulated in intestinal epithelial cells suppressed PPARalpha-mediated transactivation of Octn1 in the dark phase. 25422143

名称对应

Type IDs
Synonymous Octn1
Gene
UniProtKB-ID: S22A4_MOUSE
UniprotKB: Q9Z306
UniParc: UPI00000218DA
EMBL: AB016257, BC010590
Ensembl: ENSMUSG00000020334
KO: mmu:30805
Nucleutide sequences
EMBL-CDS: AAH10590.1, BAA36626.1
Ensembl_TRS: ENSMUST00000020586
Protein sequencees
Ensembl_PRO: ENSMUSP00000020586
RefSeq: NP_062661.1, NP_001317233.1, XP_017170077.1, XP_011247367.1, XP_006533575.1
Others
UniRef100: UniRef100_Q9Z306
UniRef90: UniRef90_Q9Z306
UniRef50: UniRef50_Q9Z306
UniGene: Mm.274590
CCDS: CCDS24689.1

全选

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研究热度

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