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30800 Mmp20

30800

Mmp20

matrix metallopeptidase 20 (enamelysin)

protein-coding

Mus musculus

基因描述

Type Description
Definition matrix metallopeptidase 20 (enamelysin)

研究结论

Date Results Publications
2019-12-14 11:27:00 polymorphisms in Ambn, Col14a1, and Mmp20 are associated with the susceptibility to dental fluorosis 30149392
2018-07-07 10:41:00 increased cadherin cleavage by transgenic MMP20 in the wild type background releases excess beta-catenin, which translocates to ameloblast nuclei to promote cell migration/invasion. Therefore, MMP20 plays a role in normal ameloblast migration through tightly controlled Wnt signaling and MMP20 overexpression disrupts this process. 27403713
2016-09-17 12:09:00 MMP-20 action guides the growth morphology of the forming hydroxyapatite crystals and enhances their crystallinity. 26513418
2014-10-04 11:00:00 Matrix metalloproteinase-20 over-expression is detrimental to enamel development 24466234
2014-01-25 11:21:00 MMP20 cleaves extracellular domains of cadherin adherens junction proteins, both E- and N-cadherin transcripts are expressed at significantly higher levels in Mmp20 null mice; in Mmp20 ablated mice N-cadherin expression persists during maturation stage 24067343

名称对应

Type IDs
Gene
UniProtKB-ID: MMP20_MOUSE
UniprotKB: P57748
UniParc: UPI0000023950
EMBL: AF156951, AF156956, AF156953, AF156949, BC152335, AF156950, AF156955, AF155933, BC152336, AF156947, AF156954, AF156952, AF156948
Ensembl: ENSMUSG00000018620
KO: mmu:30800
Nucleutide sequences
EMBL-CDS: AAF28472.1, AAF28470.1, AAI52337.1, AAI52336.1
Ensembl_TRS: ENSMUST00000034487
Protein sequencees
Ensembl_PRO: ENSMUSP00000034487
RefSeq: NP_038931.1
Others
UniRef100: UniRef100_P57748
UniRef90: UniRef90_P57748
UniRef50: UniRef50_O60882
UniGene: Mm.390121
CCDS: CCDS22809.1

全选

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研究热度

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