| Type | Description |
|---|---|
| Definition | complement factor H related 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 10:11:00 | Studies indicate an association between CFHR2-rs2986127 and acute anterior uveitis (AAU) diagnosis. | 27306586 |
| 2016-06-16 11:45:00 | Next-generation sequencing of the CFH region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR2] | 27196323 |
| 2016-04-02 11:04:00 | Studies indicate that complement factor H-related proteins (FHR1-5) may enhance complement activation, with important implications for the role of these proteins in disease. | 25979655 |
| 2014-10-18 10:19:00 | Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479. | 24333077 |
| 2014-07-12 10:52:00 | Thus CFHR2 likely acts in concert with factor H, as CFHR2 inhibits convertases while simultaneously allowing factor H assisted degradation by factor I. | 24260121 |
| Type | IDs |
|---|---|
| Synonymous | CFHL2, FHR2, HFL3 |
| Gene |
UniProtKB-ID:
FHR2_HUMAN,
A0A3B3IRW0_HUMAN,
A0A3B3IS28_HUMAN
UniprotKB:
P36980,
A0A3B3IRW0,
A0A3B3IS28
UniParc:
UPI000012A73B,
UPI000002A9AF,
UPI000387D9BD,
UPI00001B2155
EMBL:
X86566,
BC022283,
X86565,
X64877,
AL139418,
X86564,
X86567
Ensembl:
ENSG00000080910
KO:
hsa:3080
|
| Nucleutide sequences |
EMBL-CDS:
CAA60375.1,
AAH22283.1,
CAA46096.1
Ensembl_TRS:
ENST00000367415,
ENST00000496448,
ENST00000473386
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356385,
ENSP00000496889,
ENSP00000497089
RefSeq:
XP_011507761.1,
NP_005657.1,
XP_016856598.1,
XP_011507760.1,
XP_011507762.1,
XP_005245170.1,
NP_001299601.1
|
| Others |
UniRef100:
UniRef100_A0A3B3IS28,
UniRef100_A0A3B3IRW0,
UniRef100_P36980
UniRef90:
UniRef90_A0A3B3IRW0,
UniRef90_A0A2I2Z920,
UniRef90_P36980
UniRef50:
UniRef50_P36980,
UniRef50_A0A2I2Z920,
UniRef50_Q7TP43
UniGene:
Hs.632450
CCDS:
CCDS30959.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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