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3071 NCKAP1L

3071

NCKAP1L

NCK associated protein 1 like

protein-coding

Homo sapiens

基因描述

Type Description
Definition NCK associated protein 1 like

研究结论

Date Results Publications
2021-03-13 13:24:00 NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation. 32766723
2020-07-18 10:46:00 the evolutionarily conserved HEM1 protein simultaneously regulates filamentous actin (F-actin) and mTORC2 signaling to achieve equipoise in immune responses. 32647003
2010-01-21 00:00:00 versatile Hem-1-containing complexes coordinate diverse regulatory signals at the leading edge of polarized neutrophils, including but not confined to those involving Verprolin-homologous protein-dependent actin polymerization 16417406
2010-01-21 00:00:00 the Hem-1/Nap1 component of the Scar/WAVE complex localizes to propagating waves that appear to organize the leading edge of a motile neutrophil 17696648

名称对应

Type IDs
Synonymous HEM1
Gene
UniProtKB-ID: NCKPL_HUMAN
UniprotKB: P55160
UniParc: UPI00017A7FF1, UPI00001C0439
EMBL: M58285, BC093769, AC068789, BC093771, AC025570, AK300783, CH471054, AC079313
Ensembl: ENSG00000123338
KO: hsa:3071
Nucleutide sequences
EMBL-CDS: AAH93769.1, BAG62447.1, EAW96787.1, AAA35964.1, AAH93771.1
Ensembl_TRS: ENST00000545638, ENST00000293373
Protein sequencees
Ensembl_PRO: ENSP00000445596, ENSP00000293373
RefSeq: NP_005328.2, NP_001171905.1
Others
UniRef100: UniRef100_P55160
UniRef90: UniRef90_P55160
UniRef50: UniRef50_P55160
UniGene: Hs.182014
CCDS: CCDS31813.1, CCDS53799.1

全选

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研究热度

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