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307 ANXA4

307

ANXA4

annexin A4

protein-coding

Homo sapiens

基因描述

Type Description
Definition annexin A4

研究结论

Date Results Publications
2021-03-20 13:29:00 GSK3beta-Ikaros-ANXA4 signaling inhibits high-glucose-induced fibroblast migration. 32807499
2020-02-22 10:19:00 Bioinformatics analysis predicted that annexin A4 was a potential target gene of miR-203. Next, luciferase reporter assay confirmed that miR-203 could directly target annexin A4. 30837034
2018-12-22 12:13:00 ANXA4 expression was increased at both the mRNA and protein level in the drugresistant ovarian cancer cells, and ANXA4 contained a Lewis(y) structure. ANXA4 overexpression can abnormally activate signaling pathways and regulate the expression of a numbers of factors, forming a positive feedback loop to induce the chemoresistance of ovarian cancer cells. 30066907
2018-09-15 10:26:00 Annexin A4 binds to artificial membranes and generates curvature force initiated from free edges, whereas annexin A6 induces constriction force. 29158488
2018-05-05 12:06:00 Taken together, these data indicate that up-regulation of ANXA4 leads to activation of the NF-kappaB pathway and its target genes in a feedback regulatory mechanism via the p65 subunit, resulting in tumor growth in GBC. 27491820

名称对应

Type IDs
Synonymous ANX4, HEL-S-274, P32.5, PAP-II, PIG28, PP4-X, ZAP36
Gene
UniProtKB-ID: ANXA4_HUMAN, Q6P452_HUMAN, Q6LES2_HUMAN
UniprotKB: P09525, Q6P452, Q6LES2
UniParc: UPI000013D51A, UPI0000E6073A, UPI00017A6CD7, UPI0000227E53
EMBL: AC092431, BC011659, CR407681, D78152, AK315511, CH471053, M19383, BC000182, AC019206, BC063672, M82809, AC112787, AK293177, AY453398
Ensembl: ENSG00000196975
KO: hsa:307
Nucleutide sequences
EMBL-CDS: AAA51740.1, BAG56720.1, BAA11227.1, AAC41689.1, AAH11659.1, AAH00182.1, AAH63672.1, CAG28609.1, AAY14864.1, BAG37892.1, AAS47515.1, EAW99844.1
Gene_ORFName: hCG_39482
Ensembl_TRS: ENST00000536030, ENST00000394295, ENST00000409920
Protein sequencees
Ensembl_PRO: ENSP00000377833, ENSP00000441931, ENSP00000386756
RefSeq: XP_016859433.1, XP_016859432.1, NP_001307627.1, NP_001144.1, XP_024308602.1, NP_001307629.1, XP_024308603.1, NP_001352425.1, NP_001307631.1
Others
UniRef100: UniRef100_Q6P452, UniRef100_P09525
UniRef90: UniRef90_P09525, UniRef90_H0WYE7
UniRef50: UniRef50_P70075, UniRef50_P09525
UniGene: Hs.422986

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