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30696 nkx2.5

30696

nkx2.5

NK2 homeobox 5

protein-coding

Danio rerio

基因描述

Type Description
Definition NK2 homeobox 5

研究结论

Date Results Publications
2020-05-23 13:19:00 pacemaker cardiomyocytes derive from a subset of Nkx2.5+ mesoderm that responds to canonical Wnt5b signaling to initiate the cardiac pacemaker program 31402282
2020-02-22 12:16:00 identified a 42-bp heart-specific enhancer near the NOTCH1 gene and further verified its functional targeting by NKX2-5. 30919514
2018-12-01 10:03:00 results indicate that during zebrafish cardiogenesis, Foxc1a is active directly upstream of nkx2.5. 29162723
2018-07-21 10:37:00 Nkx2.5 signaling via activation of Nkx2.5-Calr-p53 signaling pathway results in cardiac dysfunction and hyperglycemia-induced cardiomyopathy. 28801532
2018-04-14 11:20:00 Nkx2-5 and nkx2.7 genes restrict proliferation of heart field progenitors in the outflow tract, delimit the number of progenitors at the venous pole and pattern the sinoatrial node acting through Isl1 repression. 29361575

名称对应

Type IDs
Synonymous nk2.5, nkx2-5, sb:eu581, zgc:111912
Gene
UniProtKB-ID: Q98872_DANRE
UniprotKB: Q98872
UniParc: UPI00000FD2C8
EMBL: U66572
KO: dre:30696
Nucleutide sequences
EMBL-CDS: AAC05229.1
Protein sequencees
RefSeq: NP_571496.2
Others
UniRef100: UniRef100_Q98872
UniRef90: UniRef90_F1RCL3
UniRef50: UniRef50_F7BSL0
UniGene: Dr.271

全选

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研究热度

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