| Type | Description |
|---|---|
| Definition | high density lipoprotein binding protein |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 12:23:00 | Our data reveal that vigilin is essential for maintenance of imprinting of IGF2 gene via functional interaction between KH1-7 domains of vigilin and zinc-finger domains of CTCF. | 29157910 |
| 2018-02-17 10:37:00 | vigilin has been shown to bind over 700 mRNAs and has been associated with cancer progression and cardiovascular disease. | 28975734 |
| 2017-05-06 20:40:00 | this study shows that vigilin (HDLBP) binds and negatively regulates MICB expression through its 5'UTR, and that vigilin downregulation in target cells leads to NK cell activation against said target cells | 28356383 |
| 2015-01-17 13:12:00 | progressively upregulated vigilin may serve as a molecular risk marker for hepatocellular carcinoma development, and targeting vigilin may help to inhibit hepatocellular carcinoma cell growth, survival and migration. | 24676454 |
| 2014-06-28 12:50:00 | CTCF may regulate vigilin behavior and thus indirectly influence the binding of HP1alpha to the satellite 2 locus | 24561205 |
| Type | IDs |
|---|---|
| Synonymous | HBP, PRO2900, VGL |
| Gene |
UniProtKB-ID:
VIGLN_HUMAN,
B2R5V9_HUMAN,
A0A024R4E5_HUMAN
UniprotKB:
Q00341,
B2R5V9,
A0A024R4E5
UniParc:
UPI00017504BD,
UPI00001AEF85,
UPI0001AE777C,
UPI0000000C28
EMBL:
AC104841,
AK312335,
BC001179,
AK300312,
CH471063,
M64098,
KF456779
Ensembl:
ENSG00000115677
KO:
hsa:3069
|
| Nucleutide sequences |
EMBL-CDS:
AAY14717.1,
BAG62064.1,
AAA35962.1,
AAH01179.1,
BAG35256.1,
EAW71255.1,
EAW71254.1,
EAW71253.1
Gene_ORFName:
hCG_33048
Ensembl_TRS:
ENST00000427183,
ENST00000391975,
ENST00000391976,
ENST00000310931
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399139,
ENSP00000312042,
ENSP00000375837,
ENSP00000375836
RefSeq:
NP_001307896.1,
XP_016859431.1,
XP_011509360.1,
XP_016859429.1,
NP_001230829.1,
NP_976221.1,
XP_024308601.1,
XP_024308600.1,
NP_005327.1,
NP_001307895.1,
XP_016859430.1,
XP_005247059.2,
XP_006712538.1,
XP_011509362.1,
NP_001307894.1
|
| Others |
UniRef100:
UniRef100_Q00341,
UniRef100_A0A024R4E5,
UniRef100_B2R5V9
UniRef90:
UniRef90_Q00341
UniRef50:
UniRef50_Q00341
UniGene:
Hs.471851,
Hs.732361
CCDS:
CCDS2547.1,
CCDS58760.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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