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3061 HCRTR1

3061

HCRTR1

hypocretin receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition hypocretin receptor 1

研究结论

Date Results Publications
2020-08-01 10:35:00 TM4 and 5 of APJ act as the interaction interface of the APJ-OX1R heterodimer, and co-internalization could be disrupted by these peptides as well. 31668922
2020-06-13 12:39:00 Study shows that homozygocity for the minor variant of the HCRTR1 gene (rs2271933, G1222A) that causes amino acid substitution (Ile408Val) was associated with aggressiveness measured with either self-reports or clinical interviews. 30742846
2020-03-28 11:47:00 A significant interaction effect between GHRL rs696217 and HCRTR1 rs2271933 was found to predict the Post-traumatic stress disorder symptoms Checklist (PCL-5) total score (P = 0.007). 30326460
2019-12-14 10:04:00 Orx1 rs10914456 variants may affect depressive symptom severity. 30596528
2019-08-03 10:37:00 Silence of OX1R completely abolished the inhibitory function of orexin in attachment of THP-1 cells. Collectively, our data suggest that orexin A ameliorated endothelial dysfunction under inflammatory stimuli. 30207631

名称对应

Type IDs
Synonymous OX1R
Gene
UniProtKB-ID: OX1R_HUMAN, A6NMV7_HUMAN
UniprotKB: O43613, A6NMV7
UniParc: UPI000059CF91, UPI0000038135
EMBL: AY062030, AC114488, AF202079, AF202078, AF202080, AF041243, AF202082, BC074796, AY070269, AF202083, AK290521, CH471059, AF202081, AF202084
Ensembl: ENSG00000121764
KO: hsa:3061
Nucleutide sequences
EMBL-CDS: BAF83210.1, AAH74796.1, AAG28020.1, EAX07602.1, AAL50221.1, AAL47214.1, AAC39601.1
Ensembl_TRS: ENST00000373706, ENST00000403528, ENST00000373705
Protein sequencees
Ensembl_PRO: ENSP00000362810, ENSP00000384387, ENSP00000362809
RefSeq: XP_024302371.1, XP_016856596.1, XP_024302372.1, XP_024302373.1, NP_001516.2, XP_024302370.1
Others
UniRef100: UniRef100_A6NMV7, UniRef100_O43613
UniRef90: UniRef90_A0A2Y9J4V8, UniRef90_O43613
UniRef50: UniRef50_P56718, UniRef50_O43613
UniGene: Hs.388226
CCDS: CCDS344.1

全选

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