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3059 HCLS1

3059

HCLS1

hematopoietic cell-specific Lyn substrate 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition hematopoietic cell-specific Lyn substrate 1

研究结论

Date Results Publications
2020-05-09 11:15:00 Hematopoietic cell-specific Lyn substrate, HCLS1, is a versatile actin-binding protein in leukocytes. (Review) 30537294
2017-12-16 11:48:00 these studies indicate HS1 plays an important role in ROR1-dependent Wnt5a-enhanced chemokine-directed leukemia-cell migration. 28465529
2015-04-18 12:02:00 SDF1alpha-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells. 25359136
2013-07-06 11:19:00 Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 and Ezrin in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 receptors. 23017497
2013-01-12 10:02:00 interaction of HCLS1 with LEF-1 is essential for G-CSF-triggered myeloid differentiation; data demonstrate the importance of HCLS1 in myelopoiesis in vitro and in vivo 23001182

名称对应

Type IDs
Synonymous CTTNL, HS1, lckBP1, p75
Gene
UniProtKB-ID: HCLS1_HUMAN
UniprotKB: P14317
UniParc: UPI00017A7941, UPI000013F884
EMBL: CR456794, X16663, BC016758, BT006824, AK298663, AK312750, AC133750
Ensembl: ENSG00000180353
KO: hsa:3059
Nucleutide sequences
EMBL-CDS: AAH16758.1, AAP35470.1, CAG33075.1, BAG35617.1, CAA34651.1, BAG60831.1
Ensembl_TRS: ENST00000314583, ENST00000495491
Protein sequencees
Ensembl_PRO: ENSP00000320176, ENSP00000418299
RefSeq: NP_001278970.2, NP_005326.3
Others
UniRef100: UniRef100_P14317
UniRef90: UniRef90_P14317
UniRef50: UniRef50_Q60598
UniGene: Hs.14601
CCDS: CCDS3003.1

全选

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