| Type | Description |
|---|---|
| Definition | HCK proto-oncogene, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:43:00 | Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma. | 32591642 |
| 2021-03-27 14:42:00 | HCK promotes glioblastoma progression by TGFbeta signaling. | 32484210 |
| 2020-10-31 13:13:00 | Membrane Anchoring of Hck Kinase via the Intrinsically Disordered SH4-U and Length Scale Associated with Subcellular Localization. | 31877324 |
| 2020-03-28 10:34:00 | These studies show that Hck and Fgr expression influences inhibitor sensitivity and the pathway to acquired resistance in Flt3-ITD+ AML. | 31790499 |
| 2019-10-12 10:39:00 | These results suggest that the axis participates in the differentiation of PTGS2(high) IFNG(low) PRF1(low) GZMB(low) FCGR3(-) NK cells in ectopic lesion microenvironment. | 29962266 |
| Type | IDs |
|---|---|
| Synonymous | JTK9, p59Hck, p61Hck |
| Gene |
UniProtKB-ID:
HCK_HUMAN,
A8K4G3_HUMAN
UniprotKB:
P08631,
A8K4G3
UniParc:
UPI00015DA782,
UPI00004709D1,
UPI000012C34E,
UPI0001C4365F,
UPI000015C528
EMBL:
BC094847,
BC108930,
AL353092,
AK290928,
AK298726,
M16592,
M16591,
BC014435,
BC114463,
X58742,
X58743,
AK026432,
AK289896,
BC113854,
BC108931,
AL049539,
CH471077,
X58741
Ensembl:
ENSG00000101336
KO:
hsa:3055
|
| Nucleutide sequences |
EMBL-CDS:
AAI08932.2,
AAI13855.2,
CAI22966.1,
BAG60878.1,
CAI22967.1,
CAI19695.1,
AAA52643.1,
EAW76393.1,
AAI08931.2,
AAI14464.2,
AAH14435.2,
CAA41565.2,
BAB15482.1,
AAH94847.2,
EAW76392.1,
CAI19694.1,
AAA52644.1,
BAF82585.1,
BAF83617.1
Ensembl_TRS:
ENST00000520553,
ENST00000629881,
ENST00000518730,
ENST00000538448
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000427757,
ENSP00000429848,
ENSP00000486627,
ENSP00000441169
RefSeq:
NP_001165600.1,
NP_001165604.1,
NP_001165602.1,
NP_001165603.1,
NP_002101.2,
NP_001165601.1
|
| Others |
UniRef100:
UniRef100_P08631,
UniRef100_A8K4G3
UniRef90:
UniRef90_P08631
UniRef50:
UniRef50_P08631
UniGene:
Hs.655210
CCDS:
CCDS54456.1,
CCDS54453.1,
CCDS33460.1,
CCDS54455.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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