| Type | Description |
|---|---|
| Definition | leucine zipper and EF-hand containing transmembrane protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-16 10:34:00 | Letm1 expression is decreased in patients with intractable TLE and a rat model of epilepsy. Down-regulation of Letm1 leads to increases mitochondrial swelling and decreased MT-CYB expression, which is associated with susceptibility to seizures. | 23645710 |
| 2015-01-31 11:53:00 | Reconstitution of LETM1 or antioxidant overexpression rescued mitochondrial Ca(2+) transport and bioenergetics | 25077561 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LETM1_RAT
UniprotKB:
Q5XIN6
UniParc:
UPI00001D0C3C
EMBL:
BC083642
Ensembl:
ENSRNOG00000016427
KO:
rno:305457
|
| Nucleutide sequences |
EMBL-CDS:
AAH83642.1
Ensembl_TRS:
ENSRNOT00000022540
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000022540
RefSeq:
NP_001005884.1
|
| Others |
UniRef100:
UniRef100_Q5XIN6
UniRef90:
UniRef90_Q9Z2I0
UniRef50:
UniRef50_O95202
UniGene:
Rn.162290
|
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29476059 |
Identification and characterization of the BRI2 interactome in the brain. Sci Rep Filipa Martins , Ana M Marafona , Cátia D Pereira , Thorsten Müller , Christina Loosse , Katharina Kolbe , Odete A B da Cruz E Silva , Sandra Rebelo |
2018-02-23 | - |
| 27669901 |
Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) forms a Ca(2+)/H(+) antiporter. Sci Rep Juan Shao , Zhenglin Fu , Yanli Ji , Xiangchen Guan , Shang Guo , Zhanyu Ding , Xue Yang , Yao Cong , Yuequan Shen |
2016-09-27 | - |
| 26975899 |
Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash activation. Cell Calcium Tingting Hou , Chongshu Jian , Jiejia Xu , August Yue Huang , Jianzhong Xi , Keping Hu , Liping Wei , Heping Cheng , Xianhua Wang |
2016-05-01 | - |
| 26316108 |
Mol Cell Proteomics Tania Martins-Marques , Sandra Isabel Anjo , Paulo Pereira , Bruno Manadas , Henrique Girão |
2015-11-01 | - |
| 25077561 |
LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation. FASEB J. Patrick J Doonan , Harish C Chandramoorthy , Nicholas E Hoffman , Xueqian Zhang , César Cárdenas , Santhanam Shanmughapriya , Sudarsan Rajan , Sandhya Vallem , Xiongwen Chen , J Kevin Foskett , Joseph Y Cheung , Steven R Houser , Muniswamy Madesh |
2014-11-01 |
Letm1,
Letm1,
LETM1
|
| 23645710 |
Association of mitochondrial letm1 with epileptic seizures. Cereb. Cortex Xiaogang Zhang , Guojun Chen , Yaodong Lu , Jing Liu , Min Fang , Jing Luo , Qingqing Cao , Xuefeng Wang |
2014-10-01 |
Letm1,
LETM1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19797662 |
Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter. Science Dawei Jiang , Linlin Zhao , David E Clapham |
2009-10-02 | - |
| 18628306 |
J. Cell. Sci. Shoko Tamai , Hiroshi Iida , Sadaki Yokota , Tomoko Sayano , Shoko Kiguchiya , Naotada Ishihara , Jun-Ichi Hayashi , Katsuyoshi Mihara , Toshihiko Oka |
2008-08-01 |
Letm2,
LETM2,
LETM1,
BCS1L
|
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 排名 | 科研单位 | 文献 |
|---|
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|
目前还没有研究热点人员