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3054 HCFC1

3054

HCFC1

host cell factor C1

protein-coding

Homo sapiens

基因描述

Type Description
Definition host cell factor C1

研究结论

Date Results Publications
2020-09-26 13:04:00 Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1. 31693902
2020-09-19 16:27:00 Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2. 32479599
2020-01-25 14:06:00 The HCF-1:ChREBP complex resides at lipogenic gene promoters, where HCF-1 regulates H3K4 trimethylation to prime recruitment of the Jumonji C domain-containing histone demethylase PHF2 for epigenetic activation of these promoters.. these findings define HCF-1's interaction with ChREBP as a previously unappreciated mechanism whereby glucose signals are both relayed to ChREBP and transmitted for epigenetic regulation 31227231
2019-04-13 12:10:00 The HCF-1PRO repeat possesses an important extended threonine-rich region that is tightly bound by the OGT tetratricopeptide-repeat region. This region confers both glycosylation and proteolytic activities to HCF-1. 30224358
2017-09-16 10:05:00 Data show that Myc boxes (MbIV) is required for the association of MYC with the abundant transcriptional coregulator host cell factor-1 (HCF-1). 26522729

名称对应

Type IDs
Synonymous CFF, HCF, HCF-1, HCF1, HFC1, MRX3, PPP1R89, VCAF
Gene
UniProtKB-ID: HCFC1_HUMAN, A6NEM2_HUMAN
UniprotKB: P51610, A6NEM2
UniParc: UPI0000142F1F, UPI0000E5B00E, UPI000036779B, UPI00033362A7, UPI000022839F
EMBL: L20010, U52112, BC063435, X79198
Ensembl: ENSG00000172534
KO: hsa:3054
Nucleutide sequences
EMBL-CDS: CAA55790.1, AAH63435.1
Ensembl_TRS: ENST00000310441, ENST00000369984
Protein sequencees
Ensembl_PRO: ENSP00000309555, ENSP00000359001
RefSeq: XP_016884960.1, XP_006724878.1, NP_005325.2, XP_006724879.1, XP_016884961.1, XP_011529449.1, XP_011529450.1
Others
UniRef100: UniRef100_A6NEM2, UniRef100_P51610
UniRef90: UniRef90_A6NEM2, UniRef90_P51610
UniRef50: UniRef50_P51610
UniGene: Hs.83634
CCDS: CCDS44020.1

全选

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