| Type | Description |
|---|---|
| Definition | fibroblast growth factor 8a |
| Date | Results | Publications |
|---|---|---|
| 2019-02-16 10:40:00 | we employ a sensitive assay of human FGF8 variants in zebrafish to demonstrate that the spectrum of isoforms of FGF8 produced by alternative splicing can provide key insights into the genetic susceptibility to human malformations | 29584859 |
| 2018-01-20 10:41:00 | Fgf8a signaling may have opposing actions on these two MG populations, they remain united in their response to Notch signaling inhibition, which stimulates both populations to enter an activated, but quiescent, state. | 28445734 |
| 2017-07-01 10:16:00 | Loss of function of both fgf3 and fgf8a lead to a striking loss of the postchordal neurocranium that can be rescued by restoring Fgf3 and Fgf8a signaling centers in the brain and mesoderm. | 27060628 |
| 2015-07-25 11:30:00 | A localized source of FGF8 placed adjacent to the nephric duct did not affect the duct migration path. | 25516335 |
| 2015-01-31 12:41:00 | Fgf8 morphogen gradients in zebrafish embryos are established by two mechanisms. Firs Fgf8 is taken up into the cell by clathrin-mediated endocytosis. After endocytosis the routing of Fgf8 from the early endosome to the late endosome shuts down signaling. | 24466061 |
| Type | IDs |
|---|---|
| Synonymous | ace, cb110, etID309886.13, fgf-8, fgf8, id:ibd5031, wu:fb73a06 |
| Gene |
UniProtKB-ID:
FGF8A_DANRE
UniprotKB:
O57341
UniParc:
UPI00000FB49C
EMBL:
BC086718,
AB256522,
BC165018,
AF051365,
CR925797,
AF034264
Ensembl:
ENSDARG00000003399
KO:
dre:30538
|
| Nucleutide sequences |
EMBL-CDS:
AAC41302.1,
AAI65018.1,
BAF34588.1,
AAH86718.1,
AAC60303.1
Ensembl_TRS:
ENSDART00000025583
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000018653
RefSeq:
NP_571356.2
|
| Others |
UniRef100:
UniRef100_O57341
UniRef90:
UniRef90_O57341
UniRef50:
UniRef50_O57341
UniGene:
Dr.478
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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