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30529 sox3

30529

sox3

SRY (sex determining region Y)-box 3

protein-coding

Danio rerio

基因描述

Type Description
Definition SRY (sex determining region Y)-box 3

研究结论

Date Results Publications
2020-02-29 11:59:00 The authors showed Sox3 functions as a regulator of Cyp19a1a expression, via 17beta-E2 linking apoptosis suppression, which is implicated in improving female fecundity. 30588557
2018-03-31 11:24:00 these data show that sox2 and sox3 exhibit intrinsic differences in promoting sensory vs. neural competence, but at high levels these factors can mimic each other to enhance both states. Regional cofactors like pax2a and fgf8 also modify sox2/3 functions. 29355523
2018-03-31 11:24:00 these findings show that sox2 and sox3 are together required for proper otic induction, but the level of expression must be tightly regulated to avoid suppression of differentiation and maintenance of pluripotency. 29355522
2012-01-21 10:36:00 significant decreases in sox3 (up to 3-fold) expression following chilling. Significant increases in expression of sox3 (up to 33-fold) during warming of chilled zebrafish embyos. 21820425
2011-04-09 11:05:00 Knockdown of fgf24 or sox3 causes severe epibranchial deficiencies but has little effect on otic development 21215261

名称对应

Type IDs
Synonymous id:ibd2036, sb:cb493, wu:fd02a08, zgc:110279
Gene
UniProtKB-ID: SOX3_DANRE, A9JSZ3_DANRE
UniprotKB: Q6EJB7, A9JSZ3
UniParc: UPI0000249EE5
EMBL: AB117960, BC155138, BX088596, AB242330, BC092845, AY316135
Ensembl: ENSDARG00000053569
KO: dre:30529
Nucleutide sequences
EMBL-CDS: AAP79985.1, BAE48584.1, AAH92845.1, BAD11369.2, AAI55139.1
Gene_ORFName: zgc:110279
Ensembl_TRS: ENSDART00000075617
Protein sequencees
Ensembl_PRO: ENSDARP00000070099
RefSeq: NP_001001811.2
Others
UniRef100: UniRef100_Q6EJB7
UniRef90: UniRef90_Q6EJB7
UniRef50: UniRef50_P48432
UniGene: Dr.104569

全选

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研究热度

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