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30512 ret

30512

ret

ret proto-oncogene receptor tyrosine kinase

protein-coding

Danio rerio

基因描述

Type Description
Definition ret proto-oncogene receptor tyrosine kinase

研究结论

Date Results Publications
2018-12-22 10:03:00 Authors observed no interaction between efn-A5b and RET from zebrafish, this lack of association indicates how complex efn-A signaling is and suggests that there may be other molecules involved in efn-A5-induced RET signaling. 29889908
2017-05-13 20:30:00 These data provide the first evidence for a physiologic role of these isoforms in RET pathway function. 27226544
2017-04-29 11:08:00 Significantly, we show that introduction of mapk10 mutations into ret heterozygotes enhanced the ENS deficit, supporting MAPK10 as a Hirschsprung disease (HSCR) susceptibility locus. Our studies demonstrate that ret heterozygous zebrafish is a sensitized model, with many significant advantages over existing murine models, to explore the pathophysiology and complex genetics of HSCR. 27902697
2012-06-16 12:08:00 RET expression is investigated within the brain of zebrafish; both RET protein and mRNA are observed. 21839141
2011-07-02 10:03:00 In animals lacking Ret or Gfra3 function, myogenic gene expression is reduced in forming opercular muscles, but not in non-opercular muscles derived from the same muscle anlagen. 21490065

名称对应

Type IDs
Synonymous c-ret, cret, etID315074.13, ret1, wu:fd13h01
Gene
UniProtKB-ID: A8E7C6_DANRE
UniprotKB: A8E7C6
UniParc: UPI0000D77D08
EMBL: BX005252
Ensembl: ENSDARG00000055305
KO: dre:30512
Nucleutide sequences
Ensembl_TRS: ENSDART00000077627
Protein sequencees
Ensembl_PRO: ENSDARP00000072093
RefSeq: NP_858048.2
Others
UniRef100: UniRef100_A8E7C6
UniRef90: UniRef90_A8E7C6
UniRef50: UniRef50_P07949
UniGene: Dr.75763

全选

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研究热度

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