| Type | Description |
|---|---|
| Definition | transcription factor 7 like 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 12:51:00 | Here, the authors study the function of zebrafish tcf7l2alternative splice variants and show that only variants that include exon five or an analogous human tcf7l2 variant can effectively provide compensatory repressor function to restore eye formation in embryos lacking tcf7l1a/tcf7l1b function. | 31829936 |
| 2015-06-20 12:30:00 | Tcf7l2 is essential for lateralized fate selection by habenular neurons that can differentiate along two alternative pathways, thereby leading to major neural circuit asymmetries. | 25201686 |
| 2014-06-28 11:11:00 | Dorsal and ventral habenulae develop in different regions of prosomere 2. In the process of ventral habenula formation, functional tcf7l2 gene activity is required and in its absence, ventral habenular neurons do not develop. | 24067090 |
| 2010-01-21 00:00:00 | Study underscores the involvement of Tcf4 in maintaining proliferative self-renewal in the intestine throughout life. | 17823612 |
| 2010-01-21 00:00:00 | In embryos, the tcf4 gene is highly regulated at the level of RNA splicing such that the variant proteins that are produced contain or lack domains proposed to be essential in repression or activation of transcription. | 12204269 |
| Type | IDs |
|---|---|
| Synonymous | tcf4 |
| Gene |
UniProtKB-ID:
Q71G54_DANRE
UniprotKB:
Q71G54
UniParc:
UPI0000001713
EMBL:
AF507956
KO:
dre:30510
|
| Nucleutide sequences |
EMBL-CDS:
AAM34689.1
|
| Protein sequencees |
RefSeq:
NP_571334.1
|
| Others |
UniRef100:
UniRef100_Q71G54
UniRef90:
UniRef90_Q71G54
UniRef50:
UniRef50_Q9NQB0-4
UniGene:
Dr.67692
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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