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304962 Atf6

304962

Atf6

activating transcription factor 6

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition activating transcription factor 6

研究结论

Date Results Publications
2019-01-05 10:09:00 The results showed that both Unfolded Protein Response (Xbp-1, its spliced variant sXbp-1, Atf-6, Chop, and Grp94) and Toll like receptor (2, 3, 4, 7 and 9) genes were significantly upregulated in the hippocampi of rats who were exposed to restraint stress. 29414031
2018-05-19 11:13:00 The findings demonstrate reciprocal regulation of the unfolded protein response, including ATF6alpha activation and endoplasmic reticulum expansion, and reduced contractile differentiation in bladder outlet obstruction occurring independently of thrombospondin-4, which however is a sensitive indicator of obstruction. 27581066
2017-02-18 10:11:00 these results confirmed that ER stress-mediated apoptosis contributes to the protection effects of naringenin against H/R injury, which is potentially involved in ATF6, IRE1alpha and PERK signaling activation. 27785700
2016-12-31 12:00:00 ATF6 upregulation is involved in the mechanism by which CIH attenuates myocardial I/R injury, possibly through upregulation of p-Akt, which is a key regulator of cardiomyocyte survival. 27035093
2016-06-04 10:30:00 Endoplasmic reticulum stress related factor ATF6 and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy. 26261584

名称对应

Type IDs
Gene
UniProtKB-ID: ATF6A_RAT
UniprotKB: G3V909
UniParc: UPI000050180A
EMBL: CH473958, AABR06076115, AABR06076113, AABR06076114, AABR06076116, BC168890, AABR06076112
Ensembl: ENSRNOG00000024632
KO: rno:304962
Nucleutide sequences
EMBL-CDS: EDM09246.1, AAI68890.1
Ensembl_TRS: ENSRNOT00000029202
Protein sequencees
Ensembl_PRO: ENSRNOP00000032766
RefSeq: XP_008767960.1, XP_017454318.1, NP_001100666.1
Others
UniRef100: UniRef100_G3V909
UniRef90: UniRef90_G3V909
UniRef50: UniRef50_P18850
UniGene: Rn.15235

全选

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研究热度

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