| Type | Description |
|---|---|
| Definition | hemoglobin subunit gamma 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34(+) HSPCs by CRISPR/Cas9 for the induction of fetal hemoglobin. | 32576837 |
| 2020-07-04 10:10:00 | a new mutation, which is a deletion of GCAG in the HBG1 promoter at position -273. This deletion could affect a binding site of a transcription factor unknown so far and thus modulate the expression of the HBG1 gene. | 31688634 |
| 2019-08-17 11:30:00 | This study explored BGLT3, an erythroid lncRNA encoded downstream of (A)gamma-globin (HBG1). BGLT3 and gamma-globin genes are dynamically cotranscribed in erythroid cells in vivo. Deletion of BGLT3 using CRISPR/Cas9 editing shows that it specifically contributes to regulation of gamma-globin genes. | 30150205 |
| 2019-05-11 10:18:00 | Some forms of hereditary persistence of fetal hemoglobin, a rare benign condition where individuals express the gamma-globin gene throughout adulthood, are caused by point mutations in the gamma-globin gene promoter at regions residing ~115 and 200 bp upstream of the transcription start site. We found that the major fetal globin gene repressors BCL11A and ZBTB7A directly bound to the sites at -115 and -200 bp, respecti... | 29610478 |
| 2018-10-27 12:02:00 | Data suggest that studying genotype frequency of the Xmn1 gammaG globin polymorphism (-158C>T ) in Siwa Oasis, Egypt can be considered as a starting point for further research targeting this community sector. | 29932071 |
| Type | IDs |
|---|---|
| Synonymous | HBG-T2, HBGA, HBGR, HSGGL1, PRO2979 |
| Gene |
UniProtKB-ID:
HBG1_HUMAN,
D9YZU8_HUMAN
UniprotKB:
P69891,
D9YZU8
UniParc:
UPI0000000B06,
UPI00000711A9
EMBL:
BC010913,
J00176,
V00514,
M91036,
V00513,
CH471064,
AF130098,
AF487523,
GU324925,
LT548098,
U01317,
M91037,
BC020719
Ensembl:
ENSG00000213934
KO:
hsa:3047
|
| Nucleutide sequences |
EMBL-CDS:
AAA58493.1,
AAB59429.1,
CAA23772.1,
EAW68804.1,
AAG35523.1,
AAA52637.1,
AAA16332.1,
CAA23771.1,
AAH10913.1,
AAH20719.1,
AAL99545.1,
ADL14496.1,
SAI82132.1
Gene_ORFName:
PRO2979
Ensembl_TRS:
ENST00000330597
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327431
RefSeq:
NP_000550.2
|
| Others |
UniRef100:
UniRef100_D9YZU8,
UniRef100_P69891
UniRef90:
UniRef90_P69892
UniRef50:
UniRef50_P69892
UniGene:
Hs.702189
CCDS:
CCDS7754.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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