| Type | Description |
|---|---|
| Definition | claudin 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 12:06:00 | Both upregulation of claudin-4 and downregulation of occludin might increase paracellular NaCl transport in the kidney, resulting in impaired pressure natriuresis in SS rats. | 29179201 |
| 2017-09-16 13:23:00 | the participation of aldosterone (ALD), and the effect of spironolactone (SPL), a mineralocorticoid receptor antagonist, on the expressions of claudin-2, -4, -5 and -8, and occludin in glomeruli, proximal and distal tubules isolated from diabetic rats, was evaluated. | 28493961 |
| 2015-11-07 10:27:00 | these results indicated that claudin-4 played a crucial role in AMPK-modulated paracellular permeability and ERK1/2 was required in AMPK-modulated tight junction barrier function in submandibular gland. | 25503106 |
| 2014-05-03 10:56:00 | elevated levels of inflammatory cytokines and chemokines in the small intestine of MTX-treated rats may contribute to inhibition of ZO-1/claudin-4 binding, and inhibition of ZO-1/claudin-4 binding may in turn lead to a reduction in claudin-4 expression. | 23963446 |
| 2014-03-01 11:33:00 | hyperosmolarity increases nuclear Sp1/c-Jun complex and the association of the complex with the Sp1 binding site, resulting in the segment-specific expression of claudin-4 in the kidney. | 23816505 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q5XIT8_RAT
UniprotKB:
Q5XIT8
UniParc:
UPI000019B61B
EMBL:
AABR07072283,
DQ294693,
CH473973,
DQ294692,
DQ294694,
BC083582,
DQ294695
Ensembl:
ENSRNOG00000001476
KO:
rno:304407
|
| Nucleutide sequences |
EMBL-CDS:
ABB88413.1,
ABB88411.1,
EDM13404.1,
AAH83582.1,
ABB88412.1,
ABB88410.1
Gene_ORFName:
rCG_21354
Ensembl_TRS:
ENSRNOT00000002003
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000002003
RefSeq:
NP_001012022.1
|
| Others |
UniRef100:
UniRef100_Q5XIT8
UniRef90:
UniRef90_O35054
UniRef50:
UniRef50_O35054
UniGene:
Rn.6830
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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