| Type | Description |
|---|---|
| Definition | histidine ammonia-lyase |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 11:01:00 | In the analysis of the genotype tissue expression (GTEx) project datasets, HAL rs17676826 C and NOXRED1 rs8012548 G alleles were significantly associated with their mRNA expression levels in sun-exposed skin of the lower leg (P = 6.62 x 10(-6) and 1.37 x 10(-7) , respectively) and in sun-not-exposed suprapubic skin (P < .001 and 1.43 x 10(-8) , respectively). | 31435991 |
| 2016-01-30 10:26:00 | Three LoF mutations in HAL were associated with increased histidine levels, which in turn were shown to be inversely related to the risk of CHD among both African Americans and European Americans. | 25575548 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | This evidence supports that the Hal gene is turned on by glucocorticoids and by glucagon either via or but prefers the pathway. | 15741241 |
| 2010-01-21 00:00:00 | histidase is upregulated during keratinocyte differentiation and that all-trans retinoic acid but not UV irradiation modulates the expression level | 18280705 |
| Type | IDs |
|---|---|
| Synonymous | HIS, HSTD |
| Gene |
UniProtKB-ID:
HUTH_HUMAN
UniprotKB:
P42357
UniParc:
UPI0002065622,
UPI000012CE8E,
UPI0002065621
EMBL:
AK298736,
BC096098,
AC007298,
AC126174,
D16626,
CH471054,
BC096099,
AB042217,
AK303544,
BC096097
Ensembl:
ENSG00000084110
KO:
hsa:3034
|
| Nucleutide sequences |
EMBL-CDS:
BAG64570.1,
BAG60883.1,
BAA04047.1,
AAH96097.1,
BAB61863.1,
AAH96099.1,
EAW97556.1,
AAH96098.1
Ensembl_TRS:
ENST00000261208,
ENST00000538703,
ENST00000541929
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446364,
ENSP00000440861,
ENSP00000261208
RefSeq:
XP_011536551.1,
NP_001245263.1,
NP_001245262.1,
XP_016874735.1,
NP_002099.1
|
| Others |
UniRef100:
UniRef100_P42357
UniRef90:
UniRef90_P42357
UniRef50:
UniRef50_P42357
UniGene:
Hs.190783,
Hs.742210
CCDS:
CCDS58264.1,
CCDS9058.1,
CCDS58265.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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