| Type | Description |
|---|---|
| Definition | POU class 6 homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 10:51:00 | We find that pouC is a multi-functional transcriptional regulator containing separable activation, repression, protein-protein interaction, and DNA binding domains. Using zebrafish heart development as a model system, we demonstrate that pouC knockdown impairs cardiac morphogenesis and affects cardiovascular function. We also find that levels of pouC expression must be fine-tuned to enable proper heart formation. | 30444277 |
| Type | IDs |
|---|---|
| Synonymous | pou[c], pouc |
| Gene |
UniProtKB-ID:
PO6F1_DANRE,
A0A2R8QIA3_DANRE
UniprotKB:
P31367,
A0A2R8QIA3
UniParc:
UPI00038377F9,
UPI0000131FA7
EMBL:
BC162146,
X68432,
CR354542,
BC162134
Ensembl:
ENSDARG00000011570
KO:
dre:30334
|
| Nucleutide sequences |
EMBL-CDS:
AAI62134.1,
CAA48481.1,
AAI62146.1
Ensembl_TRS:
ENSDART00000130338,
ENSDART00000187413
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000111302,
ENSDARP00000151917
RefSeq:
XP_017208991.1,
XP_005162353.1,
NP_571188.1
|
| Others |
UniRef100:
UniRef100_P31367,
UniRef100_A0A2R8QIA3
UniRef90:
UniRef90_P31367
UniRef50:
UniRef50_P31367
UniGene:
Dr.75078
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30444277 |
pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish. Dev. Dyn. Minoti Bhakta , Mahesh S Padanad , John P Harris , Christina Lubczyk , James F Amatruda , Nikhil V Munshi |
2019-02-01 | - |
| 26469318 |
RFX transcription factors are essential for hearing in mice. Nat Commun Ran Elkon , Beatrice Milon , Laura Morrison , Manan Shah , Sarath Vijayakumar , Manoj Racherla , Carmen C Leitch , Lorna Silipino , Shadan Hadi , Michèle Weiss-Gayet , Emmanuèle Barras , Christoph D Schmid , Aouatef Ait-Lounis , Ashley Barnes , Yang Song , David J Eisenman , Efrat Eliyahu , Gregory I Frolenkov , Scott E Strome , Bénédicte Durand , Norann A Zaghloul , Sherri M Jones , Walter Reith , Ronna Hertzano |
2015-10-15 | - |
| 25420467 |
Stem Cells Hui Zhang , Xuelong Wang , Kailun Lyu , Siqi Gao , Guan Wang , Chunxin Fan , Xin A Zhang , Jizhou Yan |
2015-03-01 |
fgfr4,
wisp2,
sox10,
sox19a,
wnt4a,
foxa2,
wnt2,
foxg1a,
wnt11r,
wnt10b,
foxn4,
hoxb5a,
pou3f3b,
hoxa2b,
pou5f3,
pou6f1,
hoxb2a,
hoxb3a,
hoxb8a,
hoxc4a,
hoxd3a,
hoxb1b,
hoxa11b,
pou3f2b,
pou3f1,
hoxd10a,
hoxd11a,
hoxb8b,
pax2a,
wif1,
pax3a,
foxa1,
sox21a,
foxd3,
foxa3,
pax6a,
pax7a,
sox11a,
six7,
bmp2a,
six3a,
bmpr1ba,
bmp15,
sox4a,
foxi1,
fgf10a,
sox2,
fgf1a,
fgf13b,
fgfr1op,
bambib,
hoxc8a,
paxip1,
bmp2k,
six1a,
fgfrl1b,
six6b,
col11a1b,
foxp2,
sox14,
col10a1a,
hoxb13a,
col11a2,
col2a1a,
bmp10,
pax1a,
col5a2a,
col11a1a,
foxf1,
foxo1b,
fgf4,
foxh1,
hoxb7a,
hoxc6b,
hoxc1a,
hoxa9a,
hoxa9b,
hoxa4a,
hoxa1a,
hoxb6b,
hoxa5a,
pou4f1,
bmpr1aa,
sox9a,
sox9b,
fgf8b,
six4b,
six4a,
foxn3,
fgf21,
fgf10b,
fgf12a,
wnt11,
wisp1b,
foxc1b,
col8a2,
foxb1b,
six2a
|
| 26426478 |
Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a. Elife Laura Yelin-Bekerman , Idan Elbaz , Alex Diber , Dvir Dahary , Liron Gibbs-Bar , Shahar Alon , Tali Lerer-Goldshtein , Lior Appelbaum |
2015-01-01 |
npvf,
kcnh4a,
zgc:171844,
pou6f1,
lhx3,
elovl7b,
gad1b,
rab5c,
slc17a6a,
lhx9,
ptgs2b,
dennd1b,
pax4,
kcna2b,
foxo4,
grpr,
kcnh4b,
npffr1l2,
hsf1,
hmx3a,
hcrt,
star,
adra1aa
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 16109975 |
The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. Ian G Woods , Catherine Wilson , Brian Friedlander , Patricia Chang , Daengnoy K Reyes , Rebecca Nix , Peter D Kelly , Felicia Chu , John H Postlethwait , William S Talbot |
2005-09-01 |
fgfr4,
pik3r3b,
trpv6,
poldip2,
dnase2,
rtf1,
ube2g1b,
ppp1r14bb,
pvalb3,
znf207b,
olig1,
sufu,
msi2a,
ppp4ca,
ppp1cb,
socs9,
nhp2,
kat8,
laptm4a,
fsta,
mthfd2,
mob1a,
dyrk1aa,
greb1l,
fn1a,
aldh9a1a.1,
cpt2,
sh3gl1a,
vps18,
arrdc1a,
sv2bb,
idh1,
sb:cb37,
tle3b,
erbb4a,
ap1g2,
parp2,
hbl3,
dhx37,
pcsk7,
rmdn3,
gtf3ab,
kif3b,
npl,
sall1b,
pard6ga,
arfgef1,
gdf5,
cog1,
casr,
slc25a28,
urb1,
ndufv3,
trip11,
casq2,
mpz,
rps9,
vars,
spry4,
ube2ia,
dlg1,
sim2,
blzf1,
copb2,
sec22ba,
tnfsf10l,
ednraa,
pklr,
vcana,
ywhag1,
jag1a,
jag2b,
jag1b,
vim,
tfap2a,
prps1a,
atic,
cyp1a,
ckbb,
psap,
gbx1,
ptk2ab,
meis1b,
mkrn2,
rbp5,
crabp2a,
ccna2,
hdac1,
csnk1a1,
mak16,
actl6a,
dtl,
stil,
pole2,
slc25a5,
cct7,
cct3,
smc4,
kif11
|
| 15177678 |
Gene F Relaix , S Molinari , M Lemonnier , B Schäfer , M Buckingham |
2004-05-26 |
Pou6f1,
pou6f1
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 9016656 |
Class III POU genes of zebrafish are predominantly expressed in the central nervous system. Nucleic Acids Res. P Spaniol , C Bornmann , G Hauptmann , T Gerster |
1996-12-15 | - |
| 8617510 |
Stable transfer of zebrafish chromosome segments into mouse cells. Genomics M Ekker , M D Speevak , C C Martin , L Joly , G Giroux , M Chevrette |
1996-04-01 |
foxa2,
wnt1,
ccne1,
eng2b,
shha,
pou6f1,
hoxc5a,
nr2f1a,
msx2b
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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