| Type | Description |
|---|---|
| Definition | POU domain, class 5, transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:04:00 | During gastrulation, the expression of the Oct4-related PouV gene pou5f3 (also called pou2), which is widely observed at earlier stages, was rapidly localized to an array of isolated spotted domains, each of which coincided with individual proneural clusters. These results suggest that pou5f3 promotes early neurogenesis in proneural clusters, but negatively regulates later neurogenesis. | 31520602 |
| 2020-07-04 11:55:00 | Results found that Oct4 is rapidly induced during zebrafish retina regeneration. It mediates a gene regulatory network during Muller glia (MG) reprogramming. The tudy reveals unique mechanistic involvement of Oct4, during MG reprogramming and cell cycle exit in zebrafish, which may also account for the inefficient retina regeneration in mammals. | 31594822 |
| 2019-06-15 11:39:00 | Pou5f3 remodels chromatin on high nucleosome affinity regions at zygotic genome activation. | 30674556 |
| 2018-09-22 11:53:00 | Western blot analysis were conducted on developing hatchlings with Oct4 antibody and at 13.6 and 21.6mugL(-1)dose,it showed over expression elucidating stimulatory role of nanosilver. In silico analysis depicted a firm interaction of nanosilver with Oct4 revealing their key role in growth stimulation of developing embryos. | 29778081 |
| 2017-12-02 11:32:00 | The authors show, at single-cell resolution in vivo, that Pou5f3 complexes with Nanog to pattern mesendoderm differentiation at the blastula stage. | 27684073 |
| Type | IDs |
|---|---|
| Synonymous | POU-2, cb197, chunp6868, etID49452.21, gp-9, gp9, oct4, pou2, pou5f1, spg, spg/pou2, wu:fd18d06 |
| Gene |
UniProtKB-ID:
PO5F1_DANRE,
A0A0R4I9C7_DANRE
UniprotKB:
Q90270,
A0A0R4I9C7
UniParc:
UPI0000167922,
UPI0000131FA5,
UPI000002B16E
EMBL:
FP089537,
X84224,
D28548
Ensembl:
ENSDARG00000044774
KO:
dre:30333
|
| Nucleutide sequences |
EMBL-CDS:
CAA59006.1,
BAA05901.1
Ensembl_TRS:
ENSDART00000065817
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000065816
RefSeq:
XP_005161160.1,
XP_005161161.1,
NP_571187.1
|
| Others |
UniRef100:
UniRef100_Q90270,
UniRef100_A0A0R4I9C7
UniRef90:
UniRef90_Q90270
UniRef50:
UniRef50_Q90270
UniGene:
Dr.258
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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